protein

Human Creatine Kinase-MM

MBS318120

100 Units

240 USD

Protein

Human Creatine Kinase-MM

[Creatine Kinase MM (CK-MM) >95% Pure]

[Purified Creatine Kinase MM (CKMM) isoenzyme fraction]

[creatine kinase; Creatine kinase M-type; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; creatine kinase, muscle; Creatine kinase M chain; M-CK]

[CKM; CKM; CKMM; M-CK; CKMM]

KCRM_HUMAN

Human heart

381

1 CK band by agarose gel isoenzyme electrophoresis. Molecular weight of the MM fraction is unknown.

Purified, Lyophilized.

0.32 mg/mL protein/vial(Coomasie)( prior to lyophilization).

Store at -20°C . Avoid multiple freeze/thaw cycles.

Specific methodologies have not been tested using this product.

Activity: Minimum 100 U/vial @37°C (measured on Dimension). Measured at 340 nm as one equimolar amount of NADH produced by coupled reaction. Specific Activity: 530 Units/mg protein. One unit will transfer one micromole of phosphate from creatine phosphate to ADP per minute at 37°C. Inactivation: Not applicable

Buffer: Lyophilized from 40mM Tris-Cl, 1mM EDTA, 10mM N-Acetyl cysteine, pH 7.5. Preservative: No

Purified Cardiac Markers

180588

AAA96609.1

P06732

Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Creatine Metabolism Pathway (106192); Metabolic Pathways (132956); Metabolism Of Amino Acids And Derivatives Pathway (106169); Regulation Of Retinoblastoma Protein Pathway (137916); Urea Cycle And Metabolism Of Amino Groups Pathway (198758); Creatine-phosphate Biosynthesis Pathway (138632)

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq]

Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Catalytic activity: ATP + creatine = ADP + phosphocreatine. Subunit structure: Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Subcellular location: Cytoplasm. Sequence similarities: Belongs to the ATP:guanido phosphotransferase family.Contains 1 phosphagen kinase C-terminal domain.Contains 1 phosphagen kinase N-terminal domain.

100 Units

240 USD