protein

CK-MM Antigen Grade

MBS318064

1 mg

375 USD

Protein

CK-MM Antigen Grade

Creatine Kinase MM (CK-MM) >95% Pure

Human Creatine Kinase, MM isoenzyme Antigen Grade

creatine kinase; Creatine kinase M-type; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; creatine kinase, muscle; Creatine kinase M chain; M-CK

CKM; CKM; CKMM; M-CK; CKMM

KCRM_HUMAN

Human skeletal muscle

381

Creatine Kinase MM (CK-MM) >95% Pure

>95% pure (SDS-PAGE)

Purified, Liquid

7.5mg/ml (modified Lowry assay, BSA standards). 8,075 IU/ml (Roche CK reagent, 37 degree C). Specific activity: 1,077 IU/mg.

Short-term store at 2 to 8 degree C. Long term store at -20 degree C or below.

Inactivation: Not applicable

Buffer: 25% (v/v) Ethylene Glycol, 10mM Tris, 1mM EDTA, pH 7.5, 5mM mercaptoethanol. Preservative: No. Warnings: Donor serum tested negative for HIV 1, HIV 2, HCV antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.

Purified Cardiac Markers

180588

AAA96609.1

P06732

43,101 Da

Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Creatine Metabolism Pathway (106192); Metabolic Pathways (132956); Metabolism Of Amino Acids And Derivatives Pathway (106169); Regulation Of Retinoblastoma Protein Pathway (137916); Urea Cycle And Metabolism Of Amino Groups Pathway (198758); Creatine-phosphate Biosynthesis Pathway (138632)

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq]

Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Catalytic activity: ATP + creatine = ADP + phosphocreatine. Subunit structure: Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Subcellular location: Cytoplasm. Sequence similarities: Belongs to the ATP:guanido phosphotransferase family.Contains 1 phosphagen kinase C-terminal domain.Contains 1 phosphagen kinase N-terminal domain.

1 mg

375 USD