catalog number :
MBS316271
products full name :
Sheep anti Toxic Shock Toxin
products short name :
Toxic Shock Syndrome Toxin
products name syn :
Sheep Antibody to Toxic Shock Syndrome Toxin (TSST)
other names :
toxic shock syndrome toxin; ATPase family AAA domain-containing protein 5; Chromosome fragility-associated gene 1 protein
other gene names :
Atad5; Frag1
uniprot entry name :
ATAD5_MOUSE
specificity :
Toxic Shock Syndrome Toxin. Specific to Toxic Shock Syndrome Toxin (TSST). Minimal cross-reactivity with staphylococcal enterotoxins A through E.
purity :
Toxin specific immunoaffinity column
form :
Affinity Purified, Lyophilized. Reconstitute with 1ml deionized water.
concentration :
1mg/ml (prior to lyophilization)
storage stability :
Store lyophilized product at 2 to 8 degree C. After reconstitution, aliquot and store at -80 degree C. If aliquoted for long term storage, fill volume should be equal to or greater than 50% of the nominal fill volume of the vial used. Avoid repeated freez
tested application :
EIA/ELISA
other info1 :
Immunogen: Toxic Shock Syndrome Toxin (TSST)
other info2 :
Buffer: Lyophilized from 0.01M phosphate, pH 7.4 containing 0.9% Sodium chloride. Preservative: No. Lyophilized: Yes
products categories :
Polyclonal Antibodies to Infectious Agents and Toxins
ncbi mol weight :
203,909 Da
ncbi pathways :
Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456!!Salmonella Infection Pathway 375172!!Salmonella Infection Pathway 375149
uniprot summary :
Function: Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis. Ref.1. Subunit structure: Interacts with RB1 predominantly in G1 phase via its LXCXE motif. Interacts with RAD9A in growing cells. The interaction with RAD9A is reduced after exposure to DNA replication-inhibiting agents. Ref.1. Subcellular location: Nucleus. Potential. Tissue specificity: Expressed ubiquitously in all cell lines like teratocarcinoma, cell lymphoma, lymphoma. Ref.1. Induction: Down-regulated by DNA replication-inhibiting agents. Post-translational modification: Phosphorylated upon DNA damage, probably by ATM or ATR. ATR may stimulate the RAD9A dissociation. Sequence similarities: Belongs to the AAA ATPase family. Sequence caution: The sequence AAH38279.2 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.The sequence CAI24765.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI25200.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI26037.1 differs from that shown. Reason: Erroneous gene model prediction.