catalog number :
MBS316175
products full name :
Rabbit A' Opioid Receptor, delta
products short name :
Opioid Receptor, delta (carboxyl terminal) (a.a. 360-372)
products name syn :
Rabbit Antibody to Human Opioid Receptor, delta (carboxyl terminal) (amino acids 360-372)
other names :
delta-type opioid receptor; Delta-type opioid receptor; delta-type opioid receptor; DOR-1; D-OR-1; OTTHUMP00000003778; delta opioid receptor 1; opioid receptor, delta 1; DOR-1
other gene names :
OPRD1; OPRD1; OPRD; OPRD
uniprot entry name :
OPRD_HUMAN
specificity :
Specific for Human Opioid Receptor, delta (carboxyl terminal) (a.a. 360-371). This antisera has been characterized by Western Blotting, ELISA, and cell staining techniques. Cross Reactivity: . Delta Opioid Receptor (360-372) : 100%. Delta Opioid Recepter : 60%. Mu Opioid Receptor (391-398) : 0%. Mu Opioid Receptor : 0%. Kappa Opioid Receptor (345-380) : 0%. Kappa Opioid Receptor: 0%
form :
Neat, Lyophilized. Reconstitute with 0.1ml of PBS which contains 10mg/ml BSA or with additional buffer for more dilute antisera.
storage stability :
Lyophilized: Store at 2 to 8 degree C (preferably in a dessicator). Reconstituted: Aliquot and store at -20 degree C.
app notes :
Suitable for Immunocytochemical and Western Immunoblotting detection of the receptor. Has been found to stain specific cells in various regions of PLP fixed rat brain sections known to express the delta opioid receptor using ABC techniques at a dilution of 1:800. Western Immunoblots using whole rat brain homogenate have been successful at a dilution of 1:800 and yielded a single band at ~55kDa. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
other info1 :
Immunogen: Peptide analogue of the carboxyl terminal of the delta opioid receptor covalently attached to a carrier protein.
other info2 :
Buffer: Not applicable. Preservative: No. Lyophilized: Yes. Important Note: Centrifuge before opening to ensure complete recovery of vial contents.
products categories :
Polyclonal Antibodies for Neuroscience
ncbi acc num :
NP_000902.3
ncbi gb acc num :
NM_000911.3
ncbi mol weight :
40,369 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!G Alpha (i) Signalling Events Pathway 119550!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class A Rhodopsin-like Pathway 198886!!Neuroactive Ligand-receptor Interaction Pathway 83053!!Neuroactive Ligand-receptor Interaction Pathway 462!!Peptide GPCRs Pathway 198897!!Peptide Ligand-binding Receptors Pathway 106358!!Signaling By GPCR Pathway 106356
uniprot summary :
Function: Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins. Subunit structure: Interacts with GPRASP1. Ref.6 Ref.7. Subcellular location: Cell membrane; Multi-pass membrane protein. Sequence similarities: Belongs to the G-protein coupled receptor 1 family.