catalog number :
MBS316162
products full name :
Rabbit A' M3 Muscarinic Rec.
products short name :
Muscarinic M3 Receptor (a.a. 580-589)
products name syn :
Rabbit Antibody to Muscarinic M3 Receptor (amino acids 580-589)
other names :
muscarinic acetylcholine receptor M3; Muscarinic acetylcholine receptor M3; muscarinic acetylcholine receptor M3; OTTHUMP00000037632; m3 muscarinic receptor; cholinergic receptor, muscarinic 3
other gene names :
CHRM3; CHRM3; HM3
uniprot entry name :
ACM3_HUMAN
specificity :
Muscarinic M3 Receptor (a.a. 580-589). Specific for Muscarinic M3 Receptor (carboxyl terminal) (a.a. 580-589). This antisera has been characterized by Western blotting, ELISA and cell staining techniques. Crossreactivity: M3 Muscarinic Receptor (580-
form :
Neat, Lyophilized. Reconstitute with 0.1ml PBS containing 10mg/ml BSA or with additional buffer for more dilute antibody.
storage stability :
Lyophilized: Store at 2-¬8 degree C (preferably in a dessicator). Reconstituted: Aliquot and store at -20 degree C.
other info1 :
Immunogen: A peptide analogue of the carboxyl terminal of the Muscarinic M3 receptor covalently attached to a carrier protein.
other info2 :
Buffer: Not applicable. Preservative: No. Lyophilized: Yes. Important Note: Centrifuge before opening to ensure complete recovery of vial contents.
products categories :
Polyclonal Antibodies for Neuroscience
ncbi acc num :
AAM18940.1
ncbi mol weight :
66,128 Da
ncbi pathways :
Amine Ligand-binding Receptors Pathway (106363); Calcium Regulation In The Cardiac Cell Pathway (198906); Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Cholinergic Synapse Pathway (217716); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Diabetes Pathways (105902); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020)
ncbi summary :
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. [provided by RefSeq]
uniprot summary :
Function: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction synapse postsynaptic cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein Ref.8. Sequence similarities: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM3 sub-subfamily.