antibody

Rabbit anti D1 Dopamine Rec.

MBS316161

0.1 ml

480 USD

polyclonal

rabbit

nonconjugated

Antibody

Rabbit anti D1 Dopamine Rec.

Dopamine D1 Receptor (a.a. 9-21)

Rabbit Antibody to Dopamine D1 Receptor (a.a. 9-21)

D(1A) dopamine receptor; D(1A) dopamine receptor; D(1A) dopamine receptor; D(1A) dopamine receptor; dopamine D1 receptor; dopamine receptor D1; Dopamine D1 receptor

DRD1; DRD1; DADR; DRD1A

DRD1_HUMAN

Polyclonal

Rabbit

446

Dopamine D1 Receptor (a.a. 9-21). Specific for Dopamine D1 Receptor (amino acids 9-21). This antisera has been characterized by immunocytochemical, Western immunoblot and ELISA techniques. Crossreactivity: D1 Dopamine Receptor (9-21) - 100%. D1 Dop

Neat, Lyophilized. Reconstitute with 0.1ml of PBS, which contains 10mg/ml BSA, or with additional buffer for more dilute antisera.

Lyophilized: Store at 2 to 8 degree C (preferably in a dessicator). Reconstituted: Aliquot and store at -20 degree C.

Immunogen: D1 (Ac-9-21-Cys^22) covalently attached to a carrier protein

Buffer: Not applicable. Preservative: No. Lyophilized: Yes. Important Note: Centrifuge before opening to ensure complete recovery of vial contents.

Polyclonal Antibodies for Neuroscience

4503383

NP_000785.1

NM_000794.3

P21728

49,293 Da

Amine Ligand-binding Receptors Pathway 106363!!Calcium Signaling Pathway 83050!!Calcium Signaling Pathway 459!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Dopamine Receptors Pathway 106366!!G Alpha (s) Signalling Events Pathway 119549!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class A Rhodopsin-like Pathway 198886!!Gap Junction Pathway 83072

This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq]

Function: This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Subunit structure: Interacts with DNAJC14 via its C-terminus. By similarity. Interacts with DRD1IP. Subcellular location: Cell membrane; Multi-pass membrane protein. By similarity. Endoplasmic reticulum membrane; Multi-pass membrane protein. By similarity. Note: Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14. Tissue specificity: Detected in caudate, nucleus accumbens and in the olfactory tubercle. Ref.1. Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

0.1 ml

480 USD