antibody

Rabbit anti Human Lactoferrin

MBS316068

2 mg

240 USD

polyclonal

rabbit

nonconjugated

ELISA, enzyme immunoassay

Antibody

Rabbit anti Human Lactoferrin

Lactoferrin

Rabbit Antibody to Human Lactoferrin

lactoferrin; Lactotransferrin; lactotransferrin; talalactoferrin; OTTHUMP00000209779; OTTHUMP00000209780; OTTHUMP00000209781; neutrophil lactoferrin; growth-inhibiting protein 12; lactotransferrin; Talalactoferrin

LTF; LTF; LF; HLF2; GIG12; LF

TRFL_HUMAN

Polyclonal

Rabbit

Human

15

Lactoferrin. Based on immunoelectrophoresis, the antibody reacts with human lactoferrin found in human milk. No antibody was detected against other milk or serum proteins, but antibodies may cross-react with lactoferrin from other species.

Isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads

Affinity Purified, Liquid

2.4mg/ml

Store at 2 to 8 degree C until opened. Prepare working dilution only prior to immediate use. Store remainder at 2 to 8 degree C under sterile conditions.

EIA/ELISA, IEP

Immunogen: Lactoferrin purified from human colostrum

Buffer: 0.01M Sodium phosphate, 0.25M Sodium chloride, pH 7.6. Preservative: No. Important Note: Centrifuge before opening to ensure complete recovery of vial contents.

Polyclonal Antibodies to Proteins and Bioactive Peptides

263312

AAB24877.1

P02788

78,182 Da

Amyloids Pathway 366238

This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Function: Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. Ref.21Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Ref.21Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. Ref.21The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Ref.21. Catalytic activity: Preferential at -Arg-Ser-Arg-Arg- - and -Arg-Arg-Ser-Arg- -, and of Z-Phe-Arg- -aminomethylcoumarin. Subunit structure: Monomer. Subcellular location: Secreted. Sequence similarities: Belongs to the transferrin family.Contains 2 transferrin-like domains.

2 mg

240 USD