catalog number :
MBS316063
products full name :
Rabbit anti Apolipoprotein AII
products short name :
Apolipoprotein AII (Apo AII)
products name syn :
Rabbit Antibody to Apolipoprotein AII (Apo AII)
other names :
Apolipoprotein A-II; Apolipoprotein A-II; apolipoprotein A-II; apolipoprotein A2; OTTHUMP00000032244; apolipoprotein A-II; Apolipoprotein A2
other gene names :
APOA2; APOA2; apoAII; Apo-AII; ApoA-II; N/A
uniprot entry name :
APOA2_HUMAN
specificity :
Apolipoprotein AII (Apo AII). Specifically binds to human Apo AII.
purity :
Human Apo AII Sepharose affinity column
form :
Affinity Purified, Liquid
concentration :
1mg/ml (OD280nm, E^0.1% = 1.35)
storage stability :
Short term (up to 1 week) store at 2 to 8 degree C. Long term store at -20 degree C. Avoid multiple freeze-thaw cycles.
tested application :
EIA/ELISA, Western Blot
app notes :
Can be used to detect the existence of Apo AII in plasma and lipoproteins, for immunoassay, immunoblot, enzyme conjugation or biotinylation. Dilution for immunoblot and ELISA: 5,000-40,000. Each laboratory should determine an optimum working titer for use
other info1 :
Immunogen: Purified Human Apo AII
other info2 :
Buffer: 75mM PBS, 75mM Sodium chloride, pH 7.2. Preservative: 0.02% Sodium azide. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
products categories :
Polyclonal Antibodies to Lipoproteins
ncbi mol weight :
11,175 Da
ncbi pathways :
Chylomicron-mediated Lipid Transport Pathway 106157!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Lipid Digestion, Mobilization, And Transport Pathway 106111!!Lipoprotein Metabolism Pathway 106156!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!PPAR Signaling Pathway 83042!!PPAR Signaling Pathway 450!!Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway 119544!!Statin Pathway 198852
ncbi summary :
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq]
uniprot summary :
Function: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Subunit structure: Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP. Ref.14 Ref.15 Ref.18. Subcellular location: Secreted. Tissue specificity: Plasma; synthesized in the liver and intestine. Post-translational modification: Phosphorylation sites are present in the extracelllular medium. Sequence similarities: Belongs to the apolipoprotein A2 family. Mass spectrometry: Molecular mass is 8701.2 Da from positions 24 - 100. Determined by MALDI. Ref.16Molecular mass is 8823.4 Da from positions 24 - 100. Determined by MALDI. Cysteinylated ApoA-II. Ref.16Molecular mass is 17421.3 Da from positions 24 - 100. Determined by MALDI. Homodimer. Ref.16Molecular mass is 17293.4 Da from positions 24 - 100. Determined by MALDI. Heterodimer with apolipoprotein A-II(1-76). Ref.16Molecular mass is 8578.3 Da from positions 24 - 99. Determined by MALDI. Ref.16Molecular mass is 17166.2 Da from positions 24 - 99. Determined by MALDI. Homodimer. Ref.16