MyBioSource

antibody

Rabbit anti Human Apo CII

MBS316056

1 mg

580 USD

polyclonal

rabbit

human

ELISA, western blot, enzyme immunoassay

MBS316056

Antibody

Rabbit anti Human Apo CII

Apolipoprotein CII (Apo CII)

Rabbit Antibody to Human Apolipoprotein CII (Apo CII)

apolipoprotein C-II; Apolipoprotein C-II; apolipoprotein C-II; apolipoprotein C2; apolipoprotein C-II; Apolipoprotein C2

APOC2; APOC2; APO-CII; APOC-II; MGC75082; APC2

APOC2_HUMAN

Polyclonal

Rabbit

101

Apolipoprotein CII (Apo CII). Specifically binds to human Apo CII.

Sepharose affinity column.

Affinity Purified, Liquid

1mg/ml (OD280nm, E^0.1% = 1.35)

Short-term store at 2 to 8 degree C. Long term store at -20 degree C.

EIA/ELISA, Western Blot

Can be used to detect the existence of Apo CII in plasma and lipoproteins; for immunoassay, immunoblot, enzyme conjugation or biotinylation. Dilution range for immunoblot and ELISA: 1:2,000 - 1:8,000. Each laboratory should determine an optimum working ti

Immunogen: Human Apolipoprotein CII

Buffer: 10mM PBS, 0.15M Sodium chloride, 1mM EDTA, pH 7.2. Preservative: 0.02% Sodium azide. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Polyclonal Antibodies to Lipoproteins

32130518

NP_000474.2

NM_000483.4

P02655

11,284 Da

Chylomicron-mediated Lipid Transport Pathway 106157!!HDL-mediated Lipid Transport Pathway 106158!!Lipid Digestion, Mobilization, And Transport Pathway 106111!!Lipoprotein Metabolism Pathway 106156!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!Statin Pathway 198852

This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq]

Function: Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Subcellular location: Secreted. Tissue specificity: Secreted in plasma. Involvement in disease: Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) [. MIM:207750]. It is an autosomal recessive trait characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. Ref.22. Sequence similarities: Belongs to the apolipoprotein C2 family.

1 mg

580 USD