antibody

Sheep anti Human Apolipoprotein (a)

MBS316055

1 mg

500 USD

polyclonal

sheep

nonconjugated

western blot, ELISA, enzyme immunoassay

Antibody

Sheep anti Human Apolipoprotein (a)

Apolipoprotein (a) (Apo (a))

Sheep Antibody to Human Apolipoprotein (a), (Apo (a))

apolipoprotein; Apolipoprotein A-II; apolipoprotein A-II; apolipoprotein A2; OTTHUMP00000032244; apolipoprotein A-II; Apolipoprotein A2

APOA2; APOA2; apoAII; Apo-AII; ApoA-II

APOA2_HUMAN

Polyclonal

Sheep

100

Apolipoprotein (a) (Apo (a)). Specifically binds to human Lp(a) and Apo(a).

Human Apo (a) Sepharose affinity column. Cross-reactivity to plasminogen was removed by passing plasminogen-Sepharose affinity column.

Affinity Purified, Liquid

1mg/ml (OD280nm, E^0.1% = 1.35)

Short-term store at 2 to 8 degree C. Long term store at -20 degree C. Avoid multiple freeze/thaw cycles.

EIA/ELISA, Western Blot

Buffer: 50mM Sodium borate, 0.15M Sodium chloride, 0.5mM EDTA, pH 7.2. Preservative: 0.02% Sodium azide. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Polyclonal Antibodies to Lipoproteins

671882

CAA28583.1

P02652

11,175 Da

Chylomicron-mediated Lipid Transport Pathway (106157); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544); Statin Pathway (198852)

This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq]

Function: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Subunit structure: Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP. Ref.14 Ref.15 Ref.18. Subcellular location: Secreted. Tissue specificity: Plasma; synthesized in the liver and intestine. Post-translational modification: Phosphorylation sites are present in the extracelllular medium. Sequence similarities: Belongs to the apolipoprotein A2 family. Mass spectrometry: Molecular mass is 8701.2 Da from positions 24 - 100. Determined by MALDI. Ref.16Molecular mass is 8823.4 Da from positions 24 - 100. Determined by MALDI. Cysteinylated ApoA-II. Ref.16Molecular mass is 17421.3 Da from positions 24 - 100. Determined by MALDI. Homodimer. Ref.16Molecular mass is 17293.4 Da from positions 24 - 100. Determined by MALDI. Heterodimer with apolipoprotein A-II(1-76). Ref.16Molecular mass is 8578.3 Da from positions 24 - 99. Determined by MALDI. Ref.16Molecular mass is 17166.2 Da from positions 24 - 99. Determined by MALDI. Homodimer. Ref.16

1 mg

500 USD