antibody

Goat anti Apo CII

MBS315854

1 mL

220 USD

polyclonal

goat

nonconjugated

western blot, ELISA, enzyme immunoassay

Antibody

Goat anti Apo CII

Apolipoprotein CII (Apo CII)

Goat anti Apo C II; Goat Antibody to Human Apolipoprotein CII (Apo CII), Recombinant

apolipoprotein C-II; Apolipoprotein C-II; apolipoprotein C-II; apolipoprotein C2; apolipoprotein C-II; Apolipoprotein C2

APOC2; APOC2; APO-CII; APOC-II; MGC75082; APC2

APOC2_HUMAN

Polyclonal

Goat

101

Apolipoprotein CII (Apo CII). Specific to human Apo CII.

Neat, Liquid

Short-term store at 2 to 8 degree C. Long term store at -20 degree C. Avoid multiple freeze/thaw cycles.

EIA/ELISA, Western Blot

Can be used for detection of Apo CII in plasma and lipoproteins, for immunoassay and immunoblot. Dilution for immunoblot and ELISA range: 1: 40,000 to 1:160,000. Each laboratory should determine an optimum working titer for use in its particular applic

Immunogen: Recombinant human Apo CII and boosted with pure human Apo CII.

Buffer: Not applicable. Preservative: 0.1% Sodium azide. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Polyclonal Antibodies to Lipoproteins

32130518

NP_000474.2

NM_000483.4

P02655

11,284 Da

Chylomicron-mediated Lipid Transport Pathway (106157); HDL-mediated Lipid Transport Pathway (106158); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Of Lipids And Lipoproteins Pathway (160976); Statin Pathway (198852)

This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq]

Function: Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Subcellular location: Secreted. Tissue specificity: Secreted in plasma. Involvement in disease: Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) [. MIM:207750]. It is an autosomal recessive trait characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. Ref.22. Sequence similarities: Belongs to the apolipoprotein C2 family.

1 mL

220 USD