MyBioSource

antibody

Goat anti Apolipoprotein CI

MBS315845

1 mg

435 USD

polyclonal

goat

human

enzyme immunoassay, ELISA, western blot

MBS315845

Antibody

Goat anti Apolipoprotein CI

Apolipoprotein CI (Apo CI)

Goat Antibody to Human Apolipoprotein CI (Apo CI)

apolipoprotein CI; Apolipoprotein C-I; apolipoprotein C-I; apo-CIB; apoC-IB; apolipoprotein C1; apolipoprotein C-I; Apolipoprotein C1

APOC1; APOC1; APOC1B

APOC1_HUMAN

Polyclonal

Goat

Apolipoprotein CI (Apo CI). Specific for Human Apo CI.

Human Apo CI Sepharose affinity column

Affinity Purified, Liquid

1mg/ml (OD280nm, E^0.1% = 1.35)

Short-term (up to 1 week) store at 2 to 8 degree C. Long term store at -20 degree C. Avoid multiple/freeze thaw cycles.

EIA/ELISA, Western Blot

Can be used for detection of Apo CI in plasma and lipoproteins, for immunoassay, immunoblotting, enzyme conjugation, or biotinylation. For use in ELISA and immunoblot, a dilution range of 1:2,000 to 1:20,000 is suggested. Each laboratory should determine

Immunogen: Purified Human Apolipoprotein CI

Buffer: 75mM PBS, pH 7.2 containing 75mM Sodium chloride, 0.5mM EDTA. Preservative: 0.02% Sodium azide. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Polyclonal Antibodies to Lipoproteins

Bjorkegren, J., et al., (2002), "Postprandial Enrichment of Remnant Lipoproteins With ApoC-I in Healthy Normolipidemic Men With Early Asymptomatic Atherosclerosis", Arterioscler Thromb. Vasc. Biol., 22: 1470-1474. Wassef, H., et

757914

P02654

9,332 Da

Statin Pathway 198852

The protein encoded by this gene is a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq]

Function: Appears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification. Ref.13. Subcellular location: Secreted. Tissue specificity: Synthesized mainly in liver and to a minor degree in intestine. Secreted in plasma. Miscellaneous: Apolipoprotein C-I is present in acidic (APOC1A) and basic (APOC1B) forms in P.paniscus, P.abelii and P.troglodytes and perhaps also in baboons and macaques. In human, the acidic form has become a pseudogene. Apo-CI makes up about 10% of the protein of the VLDL (very low density lipoprotein) and 2% of that of HDL (high density lipoprotein). Sequence similarities: Belongs to the apolipoprotein C1 family.

1 mg

435 USD