catalog number :
MBS315843
products full name :
Goat anti Apolipoprotein AII
products short name :
Apolipoprotein AII (Apo AII)
products name syn :
Goat Antibody to Apolipoprotein AII (Apo II)
other names :
Apolipoprotein A-II; Apolipoprotein A-II; apolipoprotein A-II; apolipoprotein A2; OTTHUMP00000032244; apolipoprotein A-II; Apolipoprotein A2
other gene names :
APOA2; APOA2; apoAII; Apo-AII; ApoA-II; N/A
uniprot entry name :
APOA2_HUMAN
specificity :
Apolipoprotein AII (Apo AII). Specifically binds to human Apo AII.
purity :
Human Apo AII-Sepharose affinity column and conjugated with HRP.
form :
HRP, Lyophilized. Reconstitute to 1ml with distilled water. Centrifuge product if not completely clear after standing for 1-2 hours at room temperature.
concentration :
1mg/ml (OD280nm, E^0.1% = 1.35) (prior to lyophilization)
storage stability :
Store lyophilized product at 2 to 8 degree C. After reconstitution, product is stable for several weeks at 2 to 8 degree C as an undiluted liquid. Prepare working dilution only prior to immediate use. For extended storage after reconstitution, we suggest
tested application :
EIA/ELISA, Western Blot
app notes :
Can be used for immunoblot (1:200-1:1,500) and ELISA (1:1,500 to 1:6,000). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessari
other info1 :
Immunogen: Human Apo AII
other info2 :
Buffer: Lyophilized from 50mM PBS, 0.1M Sodium chloride, pH 7.4 containing 10mg/ml BSA. Preservative: 0.01% Thimerosal. Lyophilized: Yes. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
products categories :
Polyclonal Antibodies to Lipoproteins
ncbi mol weight :
11,175 Da
ncbi pathways :
Chylomicron-mediated Lipid Transport Pathway 106157!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Lipid Digestion, Mobilization, And Transport Pathway 106111!!Lipoprotein Metabolism Pathway 106156!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!PPAR Signaling Pathway 83042!!PPAR Signaling Pathway 450!!Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway 119544!!Statin Pathway 198852
ncbi summary :
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq]
uniprot summary :
Function: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Subunit structure: Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP. Ref.14 Ref.15 Ref.18. Subcellular location: Secreted. Tissue specificity: Plasma; synthesized in the liver and intestine. Post-translational modification: Phosphorylation sites are present in the extracelllular medium. Sequence similarities: Belongs to the apolipoprotein A2 family. Mass spectrometry: Molecular mass is 8701.2 Da from positions 24 - 100. Determined by MALDI. Ref.16Molecular mass is 8823.4 Da from positions 24 - 100. Determined by MALDI. Cysteinylated ApoA-II. Ref.16Molecular mass is 17421.3 Da from positions 24 - 100. Determined by MALDI. Homodimer. Ref.16Molecular mass is 17293.4 Da from positions 24 - 100. Determined by MALDI. Heterodimer with apolipoprotein A-II(1-76). Ref.16Molecular mass is 8578.3 Da from positions 24 - 99. Determined by MALDI. Ref.16Molecular mass is 17166.2 Da from positions 24 - 99. Determined by MALDI. Homodimer. Ref.16