antibody

Rabbit anti BNP

MBS315608

0.1 mL

435 USD

polyclonal

rabbit

nonconjugated

ELISA, immunohistochemistry, radioimmunoassay, enzyme immunoassay

Antibody

Rabbit anti BNP

Brain Natriuretic Peptide (BNP)

Rabbit Antibody to Brain Natriuretic Peptide (BNP)

brain natriuretic peptide

Polyclonal

Rabbit

1

Brain Natriuretic Peptide (BNP). Specific for human and rat Brain Natriuretic Peptide (BNP). Crossreactivity: Brain Natriuretic Peptide - 100%. Human Atrial Natriuretic Peptide - 0%. ACTH (human, 1-39) - 0%. Calcitonin (human) - 0%. Vasoactivive Intestinal Peptide: 0%.

Neat, Lyophilized. Reconstitute with 0.1ml PBS containing 10mg/ml BSA or with additional buffer for more dilute antibody.

Lyophilized: Store at 2 to 8 degree C (preferably in a dessicator). Reconstituted: Aliquot and store at -20 degree C.

EIA/ELISA, Immunohistochemistry, Radioimmunoassay

The antiserum has been characterized by RIA, ELISA and cell staining techniques. Suitable for immunohistochemical techniques. Has been found to stain 3% buffered paraformaldehyde fixed rat brain sections using indirect immunofluorescent procedure at a dilution of 1:1000.

Immunogen: Synthetic human Brain Natriuretic Polypeptide covalently attached to a carrier protein (bovine thyroglobulin)

Buffer: Not applicable. Preservative: No. Lyophilized: Yes. Important Note: Centrifuge before opening to ensure complete recovery of vial contents.

Polyclonal Antibodies to Cardiac Markers

4433127

BAA04067.1

Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]

NPPB: Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. Belongs to the natriuretic peptide family. Protein type: Hormone; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 1p36.2. Cellular Component: extracellular space; protein complex; extracellular region. Molecular Function: diuretic hormone activity; hormone activity; receptor binding. Biological Process: cGMP biosynthetic process; negative regulation of angiogenesis; cell surface receptor linked signal transduction; regulation of vasodilation; regulation of blood pressure; receptor guanylyl cyclase signaling pathway; negative regulation of cell growth; regulation of vascular permeability; body fluid secretion; regulation of blood vessel size

0.1 mL

435 USD