catalog number :
MBS315578
products full name :
Goat anti CK-MM
products short name :
Creatine Kinase MM (CK-MM)
products name syn :
Goat Antibody to Human Creatine Kinase MM (CK-MM)
other names :
creatine kinase; Creatine kinase M-type; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; creatine kinase, muscle; Creatine kinase M chain; M-CK
other gene names :
CKM; CKM; CKMM; M-CK; CKMM
uniprot entry name :
KCRM_HUMAN
specificity :
Creatine Kinase MM (CK-MM). Human CK-MM
purity :
Immunoaffinity column chromatography
form :
Affinity Purified, Liquid
concentration :
7.11 mg/ml (OD280nm, E^1% = 13)
storage stability :
Store at 2 to 8 degree C.
tested application :
EIA/ELISA, LF, Immunoassay Antibody Pairs
app notes :
Suitable for use in ELISA and lateral flow assays. Forms a suitable pair with Monoclonal Antibody to CK-MB (Catalog# MBS310923).
other info1 :
Immunogen: Purified CK-MM from human skeletal muscle
other info2 :
Buffer: 10mM Sodium phosphate, 0.85% (w/v) Sodium chloride, pH 7.2 (PBS). Preservative: 0.05% (w/v) Sodium azide. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
products categories :
Polyclonal Antibodies to Cardiac Markers
ncbi acc num :
AAA96609.1
ncbi mol weight :
43,101 Da
ncbi pathways :
Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Creatine Metabolism Pathway (106192); Metabolic Pathways (132956); Metabolism Of Amino Acids And Derivatives Pathway (106169); Regulation Of Retinoblastoma Protein Pathway (137916); Urea Cycle And Metabolism Of Amino Groups Pathway (198758); Creatine-phosphate Biosynthesis Pathway (138632)
ncbi summary :
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq]
uniprot summary :
Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Catalytic activity: ATP + creatine = ADP + phosphocreatine. Subunit structure: Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Subcellular location: Cytoplasm. Sequence similarities: Belongs to the ATP:guanido phosphotransferase family.Contains 1 phosphagen kinase C-terminal domain.Contains 1 phosphagen kinase N-terminal domain.