product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti Sialoprotein
catalog :
MBS315321
quantity :
0.02 ml
price :
225 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS315321
products type :
Antibody
products full name :
Rabbit anti Sialoprotein
products short name :
Bone Sialoprotein
products name syn :
Rabbit Antibody to Human Bone Sialoprotein (BSP)
other names :
bone sialoprotein; Bone sialoprotein 2; bone sialoprotein 2; BSP II; OTTHUMP00000161175; bone sialoprotein II; cell-binding sialoprotein; integrin-binding sialoprotein; Bone sialoprotein II; BSP II; Cell-binding sialoprotein; Integrin-binding sialoprotein
other gene names :
IBSP; IBSP; BSP; BNSP; SP-II; BSP-II; BNSP
uniprot entry name :
SIAL_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
specificity :
Bone Sialoprotein. Human Bone Sialoprotein, rat Bone Sialoprotein. No cross reactivity with human Osteonectin or human Osteopontin.
form :
Neat, Lyophilized. Reconstitute in 20ul double distilled water.
storage stability :
Store lyophilized product at 2 to 8 degree C. After reconstitution, aliquot and store at -20 degree C. Avoid multiple freeze/thaw cycles.
other info1 :
Immunogen: Human Bone Sialoprotein (Bone extract)
other info2 :
Buffer: Not applicable. Preservative: No. Lyophilized: Yes. Important Note: Vial Contains Small Quantity. Centrifuge Product Before Opening!
products categories :
Polyclonal Antibodies for Bone and Calcium Metabolism
ncbi gi num :
292494
uniprot acc num :
P21815
ncbi mol weight :
35,148 Da
ncbi pathways :
ECM-receptor Interaction Pathway 83068!!ECM-receptor Interaction Pathway 479!!Focal Adhesion Pathway 198795!!Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!Integrin Cell Surface Interactions Pathway 106110!!Osteoblast Signaling Pathway 198842
ncbi summary :
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq]
uniprot summary :
Function: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment. Subcellular location: Secreted. Post-translational modification: N-glycosylated; glycans consist of sialated and core-fucosylated bi-, tri- and tetraantennary chains. Ref.6O-glycosylated at eight sites; mucin-type glycans contain Gal, GlcNAc, GalNAc and terminal NeuAc. Ref.6Sulfated on either Tyr-313 or Tyr-314. Miscellaneous: It is possible that the segments of clustered carboxyl groups mediate the strong binding to hydroxyapatite.
size :
0.02 ml
price :
225 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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