catalog number :
MBS315301
products full name :
Rabbit anti Calcitonin
products short name :
Calcitonin
products name syn :
Rabbit Antibody to Human Calcitonin
other names :
calcitonin; Calcitonin; calcitonin; calcitonin gene-related peptide 1; katacalcin; calcitonin 1; alpha-type CGRP; OTTHUMP00000216318; OTTHUMP00000216319; OTTHUMP00000216320; OTTHUMP00000216321; calcitonin gene-related peptide I; calcitonin/calcitonin-related polypeptide, alpha; calcitonin-related polypeptide alpha; Calcitonin carboxyl-terminal peptide; CCP; PDN-21
other gene names :
CALCA; CALCA; CT; KC; CGRP; CALC1; CGRP1; CGRP-I; MGC126648; CALC1
uniprot entry name :
CALC_HUMAN
specificity :
Calcitonin. Human Calcitonin. Does not cross react with human Catacalcin or CGrP.
form :
Neat, Lyophilized. Reconstitute in 20ul double distilled water.
storage stability :
Store lyophilized product at 2 to 8 degree C. After reconstitution, aliquot and store at -20 degree C. Avoid multiple freeze/thaw cycles.
other info1 :
Immunogen: Synthetic human Calcitonin BSA conjugated.
other info2 :
Buffer: Not applicable. Preservative: No. Lyophilized: Yes. Important Note: Vial Contains Small Quantity. Centrifuge Product Before Opening!
products categories :
Polyclonal Antibodies for Bone and Calcium Metabolism
ncbi acc num :
CAA26189.1
ncbi mol weight :
15,466 Da
ncbi pathways :
Amyloids Pathway 366238!!Calcitonin-like Ligand Receptors Pathway 106379!!Class B/2 (Secretin Family Receptors) Pathway 106378!!G Alpha (s) Signalling Events Pathway 119549!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!Myometrial Relaxation And Contraction Pathways 198759!!Signaling By GPCR Pathway 106356
ncbi summary :
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
uniprot summary :
Function: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.Katacalcin is a potent plasma calcium-lowering peptide. Subcellular location: Secreted. Sequence similarities: Belongs to the calcitonin family.