MyBioSource

antibody

MAb to CRP

MBS313139

1 mg

280 USD

monoclonal

mouse

human

ELISA, enzyme immunoassay

MBS313139

Antibody

MAb to CRP

C Reactive Protein (CRP)

Monoclonal Antibody to Human C Reactive Protein (CRP)

C-reactive protein; C-reactive protein; C-reactive protein; pentraxin 1; C-reactive protein, pentraxin-related; N/A

CRP; CRP; PTX1; PTX1

CRP_HUMAN

Monoclonal

IgG2a

108-7G4.1D2

Mouse

Human

224

C Reactive Protein (CRP) (Human CRP. Recognizes antigen both in the presence and in the absence (samples containing EDTA) of Ca2+.)

> 90% pure (SDS-PAGE). Protein A Chromatography Product is 0.2 um filtered.

Purified, Liquid

6.2 mg/mL (OD280nm, E0.1% = 1.4)

Short term (up to 7 days) store at 2-8 degree C. Long term, aliquot and store at -20 degree C. Avoid multiple freeze/thaw cycles.

ELISA (EIA)

Preservative: 0.05% Sodium Azide. Immunogen: Purified Human CRP

Affinity Constant: Not Determined. Buffer: 10 mM Sodium Phosphate, 150 mM Sodium Chloride, pH 7.4 + 0.2

Monoclonal Antibodies to Cardiac Markers

30224

CAA39671.1

P02741

25,039 Da

Classical Antibody-mediated Complement Activation Pathway 106409!!Complement Cascade Pathway 106405!!Creation Of C4 And C2 Activators Pathway 106407!!IL6-mediated Signaling Events Pathway 137932!!Immune System Pathway 106386!!Initial Triggering Of Complement Pathway 106406!!Innate Immune System Pathway 106387!!Selenium Pathway 198825

The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]

Function: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Cofactor: Binds 2 calcium ions per subunit. Subunit structure: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits. Subcellular location: Secreted. Tissue specificity: Found in plasma. Induction: The concentration of CRP in plasma increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL1/interleukin-1 and IL6//interleukin-6. Miscellaneous: This protein owes its name to its ability precipitate pneumococcal C-polysaccharide in the presence of calcium. Sequence similarities: Belongs to the pentaxin family.Contains 1 pentaxin domain. Mass spectrometry: Molecular mass is 23028 Da from positions 19 - 224. Determined by MALDI. Ref.15Molecular mass is 22930 Da from positions 19 - 223. Determined by MALDI. Ref.15

1 mg

280 USD