MyBioSource

antibody

MAb to Cadherin-17 (24-132)

MBS313038

1 mg

660 USD

monoclonal

mouse

human

western blot, enzyme immunoassay, ELISA

MBS313038

Antibody

MAb to Cadherin-17 (24-132)

Cadherin-17

Monoclonal Antibody to Human Cadherin-17 (CDH17), amino acids 24-132.

cadherin-17; Cadherin-17; cadherin-17; LI cadherin; LI-cadherin; cadherin-16; HPT-1 cadherin; liver-intestine cadherin; human peptide transporter 1; intestinal peptide-associated transporter HPT-1; human intestinal peptide-associated transporter HPT-1; cadherin 17, LI cadherin (liver-intestine); Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin

CDH17; CDH17; HPT1; CDH16; HPT-1; LI-cadherin

CAD17_HUMAN

Monoclonal

IgG2a

B1381M

Mouse. Hybridization of Sp2/0 myeloma cells with spleen cells from BALB/c mice.

832

Cadherin-17 (a.a. 24-132) (Human Cadherin-17, amino acids 24-132.)

> 90% pure (SDS-PAGE). Protein A Chromatography

Purified, Liquid

Store at 2-8 degree C.

ELISA (EIA), Western Blot (WB)

Preservative: 0.1% Sodium Azide. Immunogen: Recombinant fusion of CDH17 (a.a. 24-132) peptide and human thioredoxin.

Affinity Constant: Not Determined. Buffer: PBS, pH 7.4

Monoclonal Antibodies for Cancer Research

221316595

NP_001138135.1

NM_001144663.1

Q12864

92,219 Da

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. Ref.1. Subcellular location: Cell membrane; Single-pass type I membrane protein . Potential. Tissue specificity: Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. Ref.1. Sequence similarities: Contains 7 cadherin domains.

1 mg

660 USD