catalog number :
MBS312720
products full name :
MAb to Human IFN-beta
products short name :
[Interferon beta]
products name syn :
[Interferon beta (IFN-beta)]
other names :
[interferon beta; Interferon beta; interferon beta; IFN-beta; OTTHUMP00000021131; fibroblast interferon; interferon, beta 1, fibroblast; Fibroblast interferon]
products gene name :
[IFN-beta]
other gene names :
[IFNB1; IFNB1; IFB; IFF; IFNB; MGC96956; IFB; IFNB]
uniprot entry name :
IFNB_HUMAN
specificity :
Interferon beta (IFN-beta)
purity :
Protein A chromatography
form :
Purified, Lyophilized. Reconstitute with 0.5ml sterile water. Mix gently and wash sides of vial and wait 30-60 seconds before use.
concentration :
1mg/ml (prior to lyophilization)
storage stability :
Store lyophilized product at 2-8 degree C. After reconstitution, aliquot and store at -20 degree C.
tested application :
ELISA, Western Blot, Immunohistochemistry, Immunoprecipitation
app notes :
Each laboratory should determinmed an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
other info1 :
Immunogen: Recombinant Human IFN-b. Species Specificity: Human IFN-beta. Affinity Constant: Not determined
other info2 :
Buffer: Lyophilized from PBS. Preservative: No Preservative
products categories :
Monoclonal Antibodies to Cytokines and Growth Factors
products description :
MAb to Human IFN-beta. Monoclonal Antibody to Human Interferon beta (IFN-beta)
ncbi acc num :
NP_002167.1
ncbi gb acc num :
NM_002176.2
ncbi pathways :
Chagas Disease (American Trypanosomiasis) Pathway (147809); Chagas Disease (American Trypanosomiasis) Pathway (147795); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Cytokines And Inflammatory Response Pathway (198794); Cytosolic DNA-sensing Pathway (125137); Cytosolic DNA-sensing Pathway (124833); Factors Involved In Megakaryocyte Development And Platelet Production Pathway (187196); Hemostasis Pathway (106028)
uniprot summary :
Function: Has antiviral, antibacterial and anticancer activities. Subunit structure: Monomer. Subcellular location: Secreted. Pharmaceutical use: Available under the names Avonex (Biogen), Betaseron (Berlex) and Rebif (Serono). Used in the treatment of multiple sclerosis (MS). Betaseron is a slightly modified form of IFNB1 with two residue substitutions. Sequence similarities: Belongs to the alpha/beta interferon family.