catalog number :
MBS312512
products full name :
MAb to Human Glypican-1
products short name :
Glypican-1 (GPC1)
products name syn :
Monoclonal Antibody to Human Glypican-1 (GPC1)
other names :
glypican-1; Glypican-1; glypican-1; OTTHUMP00000164497; OTTHUMP00000201548; glypican proteoglycan 1; glypican 1
other gene names :
GPC1; GPC1; FLJ38078; glypican
uniprot entry name :
GPC1_HUMAN
host :
Host: Mouse. Source: Ascites
specificity :
Glypican-1 (GPC1). Recognizes native and recombinant human and mouse glypican-1.
purity :
Protein G chromatography
storage stability :
Upon receipt, store at -20 degree C. Avoid multiple freeze/thaw cycles.
tested application :
EIA/ELISA, Western Blot, Immunofluorescence Assay
app notes :
Suitable for use in ELISA (1-5ug/ml), Immunoblotting (1-10ug/ml) and Immunofluorescence (1-10ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other application have not been tested but use in such assays should not necessarily be excluded.
other info1 :
Immunogen: Recombinant full-length human glypican-1. Affinity Constant: Not determined
other info2 :
Buffer: PBS, pH 7.4. Preservative: No. Important Note: Centrifuge before opening to ensure complete recovery of vial contents.
products categories :
Monoclonal Antibodies for Cancer Research
ncbi acc num :
NP_002072.2
ncbi gb acc num :
NM_002081.2
ncbi mol weight :
61,680 Da
ncbi pathways :
Activation Of Rac Pathway (119530); Axon Guidance Pathway (105688); Glypican 1 Network Pathway (138010); Glypican Pathway (138083); Inactivation Of Cdc42 And Rac Pathway (119529); Role Of Abl In Robo-Slit Signaling Pathway (119531); Signaling By Robo Receptor Pathway (119527)
ncbi summary :
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq]
uniprot summary :
Function: Cell surface proteoglycan that bears heparan sulfate. Subcellular location: Cell membrane; Lipid-anchor GPI-anchor; Extracellular side. Secreted glypican-1: Secreted extracellular space. Post-translational modification: This cell-associated glypican is further processed to give rise to a medium-released species. Sequence similarities: Belongs to the glypican family.