catalog number :
MBS312483
products full name :
MAb to CEA
products short name :
[Carcinoembryonic Antigen (CEA)]
products name syn :
[Monoclonal Antibody to Human Carcinoembryonic Antigen (CEA)]
other names :
[carcinoembryonic antigen; Carcinoembryonic antigen; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)]
other gene names :
[CEACAM6; CEA; NCA; CEAL; CD66c; CEACAM6]
uniprot entry name :
Q13985_HUMAN
specificity :
Carcinoembryonic Antigen (CEA). CEA, epitope specificity group I. Does not crossreact with human leukocytes in cytofluorometry. Staining in immunohistochemistry:. Brightness - 80. Cytoplasmic staining - 3+. Membrane staining - 2+. Background - 2+. Staining of mucus - 2+
purity :
>90% pure (SDS-PAGE). Ion exchange chromatography
concentration :
4.5 mg/ml (OD280nm, E^0.1% = 1.4)
storage stability :
Store at 2 to 8 degree C. DO NOT FREEZE!
tested application :
EIA/ELISA, Immunohistochemistry
app notes :
Recommended antibody pair for sandwich immunoassay:. Capture: MBS312483; Detection: MBS312479
other info1 :
Immunogen: Human natural tumor-derived purified CEA antigen. Affinity Constant: Not determined
other info2 :
Buffer: 10mM Tris, pH 7.5 containing 0.15M Sodium chloride. Preservative: 0.05% Sodium azide. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
products categories :
Monoclonal Antibodies for Cancer Research
ncbi acc num :
AAA51971.1
ncbi mol weight :
15,545 Da
ncbi summary :
Carcinoembryonic antigen (CEA; MIM 114890) is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma. An apparent lack of absolute cancer specificity for CEA probably results in part from the presence in normal and neoplastic tissues of antigens that share antigenic determinants with the 180-kD form of CEA (Barnett et al., 1988 [PubMed 3220478]). For background information on the CEA family of genes, see CEACAM1 (MIM 109770).[supplied by OMIM]
uniprot summary :
CEACAM6: Belongs to the immunoglobulin superfamily. CEA family. Protein type: Membrane protein, integral; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 19q13.2. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: protein binding. Biological Process: cell-cell signaling; signal transduction; blood coagulation; leukocyte migration