catalog number :
MBS312137
products full name :
MAb to E-Cadherin
products short name :
Cadherin-E 123kDa (L-CAM)
products name syn :
Monoclonal Antibody to E-Cadherin
host :
Host: Mouse. Hybridization of SP2/0 myeloma cells with spleen cells from Balb/c mice. Source: Ascites
specificity :
Cadherin-E 123kDa (L-CAM). E-Cadherin (also called cell CAM 120/180 or L-CAM) is a 123kDa molecule of the cadherin family which mediates Ca2+ dependent homotypic adhesion between epithelial cells. (1,2). Recognizes E-cadherin expressed on non-neuronal e
purity :
Protein A chromatography
form :
Purified, Lyophilized. Reconstitute with 1ml of distilled water.
storage stability :
Store lyophilized product at 2 to 8 degree C. After reconstitution, aliquot and store at -20 degree C. Avoid multiple freeze/thaw cycles. The addition of 0.1% (w/v) sodium azide is recommended for storage of the reconstituted product for up to one month a
app notes :
Immunoprecipitaion. Immunohistochemistry. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
other info1 :
Immunogen: Human breast carcinoma cell line T47D. Affinity Constant: Not determined.
other info2 :
Buffer: Lyophilized from PBS with 1mg/ml BSA. Preservative: No. Lyophilized: Yes
products categories :
Monoclonal Antibodies to Proteins and Bioactive Peptides
products references :
Nagafuchi, A., et al., (1987), "Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA", Nature, 329, 341-342. Geiger, B., et al., (1992), "Cadherins", Annu. Rev. Cell Biol., 8, 307-332.