catalog number :
MBS312040
products full name :
MAb to CD9
products short name :
[CD9]
products name syn :
[Monoclonal Antibody to Human CD9]
other names :
[CD9 antigen; CD9 antigen; CD9 antigen; 5H9 antigen; tetraspanin-29; BA-2/p24 antigen; CD9 antigen (p24); OTTHUMP00000041574; OTTHUMP00000041575; OTTHUMP00000041576; OTTHUMP00000238624; leukocyte antigen MIC3; motility related protein-1; cell growth-inhibiting gene 2 protein; CD9 molecule; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24]
other gene names :
[CD9; CD9; MIC3; MRP-1; BTCC-1; DRAP-27; TSPAN29; FLJ99568; TSPAN-29; MIC3; TSPAN29]
uniprot entry name :
CD9_HUMAN
purity :
Protein A chromatography
storage stability :
Store (up to 1 year) at 2 to 8 degree C.
tested application :
Immunohistochemistry - Formalin, Immunoprecipitation, Western Blot
other info1 :
Immunogen: Human platelet glycoprotein. Affinity Constant: Not determined. Specificity Notes: Reacts with a 25kD molecular weight band on gels of non-reduced platelet membranes and immunoprecipitates a similar band from I125-labelled platelets. The antigen is expressed on eosinophils, granulocytes, monocytes and numerous stromal cells.This CD9 antigen belongs to the TM4 superfamily of cell surface proteins with the N-and C-terminal cytoplasmically located. Reacts immunohistochemically on frozen section of platelets, monocytes and pre-B cells with differential staining on lymphoid and epithelial tissues. Reacts with human, rabbit and mouse.
other info2 :
Buffer: PBS containing 1mg/ml BSA. Preservative: 0.1% Sodium azide. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
products categories :
Monoclonal Antibodies to Human CDs
products references :
Leucocyte Typing IV, Oxford University Press, (1989). Leucocyte Typing V, Oxford University Press (1995). Boucheix, C., et al., (1990), J. Biol. Chem. 266, 117-122. Lanza, F., et al., (1990), J. Bio
ncbi acc num :
NP_001760.1
ncbi gb acc num :
NM_001769.3
ncbi mol weight :
25,416 Da
ncbi pathways :
Formation Of Platelet Plug Pathway (106029); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Hemostasis Pathway (106028); Platelet Activation Pathway (106034); Platelet Degranulation Pathway (106050); Response To Elevated Platelet Cytosolic Ca2+ Pathway (106048); A6b1 And A6b4 Integrin Signaling Pathway (138008)
ncbi summary :
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq]
uniprot summary :
Function: Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion. Ref.11 Ref.12 Ref.13. Subunit structure: Forms both disulfide-linked homodimers and higher homooligomers as well as heterooligomers with other members of the tetraspanin family. Associates with CR2/CD21 and with PTGFRN/CD9P1. Interacts directly with IGSF8. Ref.14 Ref.16 Ref.17. Subcellular location: Membrane; Multi-pass membrane protein. Tissue specificity: Expressed by a variety of hematopoietic and epithelial cells. Post-translational modification: Protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids. Sequence similarities: Belongs to the tetraspanin (TM4SF) family.