catalog number :
MBS311954
products full name :
MAb to beta-Defensin-1 (a.a. 1-36)
products short name :
Defensin, beta-1 (a.a. 1-36)
products name syn :
Monoclonal Antibody to Human Defensin beta-1 (amino acids 1-36)
other names :
Defensin, beta 1; Beta-defensin 1; beta-defensin 1; BD-1; beta-defensin-1; OTTHUMP00000159500; defensin, beta 1; Defensin, beta 1
other gene names :
DEFB1; DEFB1; BD1; HBD1; DEFB-1; DEFB101; MGC51822; BD1; HBD1
uniprot entry name :
DEFB1_HUMAN
host :
Host: Mouse. Source: Cell Culture
specificity :
Defensin, beta-1 (a.a. 1-36). Synthetic human beta-Defensin 1 (a.a. 1-36).
purity :
Protein A chromatography
form :
Purified, Lyophilized. Reconstitute in 10ul double distilled water.
concentration :
1mg/ml (prior to lyophilization)
storage stability :
Store lyophilized product at 2 to 8 degree C. After reconstitution, store at -20 degree C. Avoid multiple freeze/thaw cycles.
tested application :
EIA/ELISA, Western Blot
other info1 :
Immunogen: Synthetic human beta-Defensin 1 (a.a. 1-36). (DHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK). Affinity Constant: Not determined.
other info2 :
Buffer: Lyophilized from 50mM Tris, pH 7.4. Preservative: No. Lyophilized: Yes. Important Note: Vial Contains Small Quantity. Centrifuge Product Before Opening!
products categories :
Monoclonal Antibodies to Cytokines and Growth Factors
products references :
Zucht, H.D., et al., (1998), "Human beta-defensin-1: A urinary peptide present in variant molecular forms and its putative functional implication", Eur. J. Med. Res., 3:315-323.
ncbi mol weight :
7,420 Da
ncbi pathways :
Beta Defensins Pathway (530759); Defensins Pathway (530757); Immune System Pathway (106386); Innate Immune System Pathway (106387)
ncbi summary :
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Has bactericidal activity. Subcellular location: Secreted. Tissue specificity: Plasma. Sequence similarities: Belongs to the beta-defensin family. Mass spectrometry: Molecular mass is 3928 0.5 Da from positions 33 - 68. Determined by ESI. Ref.5