catalog number :
MBS311596
products full name :
MAb to CK-BB
products short name :
[Creatine Kinase BB (CK-BB)]
products name syn :
[Monoclonal Antibody to Human Creatine Kinase BB (CK-BB)]
other names :
[Creatine kinase B-type; Creatine kinase B-type; creatine kinase B-type; creatine kinase-B; creatine kinase B chain; creatine kinase, brain; B-CK; Creatine kinase B chain]
other gene names :
[CKB; CKB; B-CK; CKBB; CKBB]
uniprot entry name :
KCRB_HUMAN
specificity :
Creatine Kinase BB (CK-BB). Human CK-BB
purity :
>90% pure (SDS-PAGE). Protein A chromatography. Product is 0.2um filtered.
concentration :
4.92mg/ml (OD280nm, E^0.1% = 1.4)
storage stability :
Short term (up to 7 days) store at 2 to 8 degree C. Long term, aliquot and store at -20 degree C. If aliquoted for long term storage, fill volume should be equal to or greater than 50% of the nominal fill volume of the vial used. Avoid repeated freeze/thaw.
app notes :
Specific methodologies have not been tested using this product.
other info1 :
Source: Ascites. Immunogen: Source: Human Brain. Affinity Constant: Not determined.
other info2 :
Buffer: 10mM Phosphate, pH 7.4 containing 150mM Sodium Chloride. Preservative: 0.05% Sodium Azide. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
products categories :
Monoclonal Antibodies to Cardiac Markers
ncbi pathways :
Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Creatine Metabolism Pathway (106192); Metabolic Pathways (132956); Metabolism Of Amino Acids And Derivatives Pathway (106169); Urea Cycle And Metabolism Of Amino Groups Pathway (198758); Creatine-phosphate Biosynthesis Pathway (138632)
ncbi summary :
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq]
uniprot summary :
Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Catalytic activity: ATP + creatine = ADP + phosphocreatine. Subunit structure: Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Subcellular location: Cytoplasm. Sequence similarities: Belongs to the ATP:guanido phosphotransferase family.Contains 1 phosphagen kinase C-terminal domain.Contains 1 phosphagen kinase N-terminal domain.