antibody

MAb to Lactoferrin

MBS311182

1 mg

400 USD

monoclonal

mouse

nonconjugated

[LF2B8]

western blot, ELISA, enzyme immunoassay

Antibody

MAb to Lactoferrin

[Lactoferrin]

[Monoclonal Antibody to Human Lactoferrin]

[lactoferrin; Lactotransferrin; lactotransferrin; talalactoferrin; OTTHUMP00000209779; OTTHUMP00000209780; OTTHUMP00000209781; neutrophil lactoferrin; growth-inhibiting protein 12; lactotransferrin; Talalactoferrin]

[LTF; LTF; LF; HLF2; GIG12; LF]

TRFL_HUMAN

Monoclonal

IgG1

[LF2B8]

Mouse

15

Lactoferrin. Lactoferrin, human. Reacts in immunoblotting of whole serum proteins with a band of 77kD. Weak crossreactivity with human transferrin. Does not cross-react with other serum proteins.

>=95% pure (SDS-PAGE). Protein G chromatography

Purified, Liquid

3.0 mg/ml (OD280nm, E 0.1% = 1.4)

Store at 2 to 8 degree C.

EIA/ELISA, Immunoassay Antibody Pairs, Western Blot

Detection of lactoferrin. Suitable for use in ELISA and Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Source: Ascites. Immunogen: Purified lactoferrin from human milk. Affinity Constant: Not determined

Buffer: PBS, pH 7.4. Preservative: 0.09% Sodium azide. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Monoclonal Antibodies to Proteins and Bioactive Peptides

263312

AAB24877.1

P02788

78,182 Da

Amyloids Pathway (366238)

This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Function: Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. Ref.21Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Ref.21Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. Ref.21The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Ref.21. Catalytic activity: Preferential at -Arg-Ser-Arg-Arg- - and -Arg-Arg-Ser-Arg- -, and of Z-Phe-Arg- -aminomethylcoumarin. Subunit structure: Monomer. Subcellular location: Secreted. Sequence similarities: Belongs to the transferrin family.Contains 2 transferrin-like domains.

1 mg

400 USD