MAb to Lactoferrin | MyBioSource MBS311072 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

MAb to Lactoferrin

catalog :

MBS311072

quantity :

1 mg

price :

350 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1A1

reactivity :

human

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS311072

products type :

Antibody

products full name :

MAb to Lactoferrin

products short name :

Lactoferrin

products name syn :

Monoclonal Antibody to Human Lactoferrin

other names :

lactoferrin; Lactotransferrin; lactotransferrin; talalactoferrin; OTTHUMP00000209779; OTTHUMP00000209780; OTTHUMP00000209781; neutrophil lactoferrin; growth-inhibiting protein 12; lactotransferrin; Talalactoferrin

other gene names :

LTF; LTF; LF; HLF2; GIG12; LF

uniprot entry name :

TRFL_HUMAN

clonality :

Monoclonal

isotype :

IgG1, kappa

clone :

1A1

host :

Host: Mouse. Hybridization of Sp2/0 myeloma cells with spleen cells from BALB/c mice. Source: Ascites

reactivity :

Human

sequence length :

specificity :

Lactoferrin. Reacts to lactoferrin.

purity :

>=95% pure (SDS-PAGE). Protein G Sepharose chromatography

form :

Purified, Liquid

concentration :

4.3mg/ml (OD280nm, E^0.1% = 1.4)

storage stability :

Store at 2 to 8 degree C.

tested application :

EIA/ELISA, Immunoassay Antibody Pairs, Western Blot

app notes :

Recommended pair for sandwich immunoassay: Capture: MBS311182 - Detection: MBS311072

other info1 :

Immunogen: Purified lactoferrin from human milk. Affinity Constant: Not determined

other info2 :

Buffer: PBS, pH 7.4. Preservative: 0.1% Sodium azide. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

products categories :

Monoclonal Antibodies to Proteins and Bioactive Peptides

ncbi gi num :

263312

ncbi acc num :

AAB24877.1

uniprot acc num :

P02788

ncbi mol weight :

78,182 Da

ncbi pathways :

Amyloids Pathway (366238)

ncbi summary :

This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

uniprot summary :

LTF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Belongs to the transferrin family. 2 isoforms of the human protein are produced by alternative promoter. Protein type: EC 3.4.21.-; Secreted, signal peptide; Protease; Secreted. Chromosomal Location of Human Ortholog: 3p21.31. Cellular Component: extracellular space; specific granule; cytoplasm; extracellular region; nucleus; secretory granule. Molecular Function: heparin binding; protein serine/threonine kinase activator activity; protein binding; ferric iron binding; DNA binding; iron ion binding; serine-type endopeptidase activity. Biological Process: negative regulation of lipopolysaccharide-mediated signaling pathway; interaction with host; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; positive regulation of toll-like receptor 4 signaling pathway; antifungal humoral response; proteolysis; iron ion transport; humoral immune response; activation of NF-kappaB transcription factor; regulation of cytokine production; retinal homeostasis; positive regulation of osteoblast differentiation; negative regulation of viral genome replication; innate immune response in mucosa; response to host immune response; positive regulation of osteoblast proliferation; antibacterial humoral response; regulation of tumor necrosis factor production; iron assimilation by chelation and transport; negative regulation of viral reproduction; negative regulation of ATPase activity; negative regulation of apoptosis

size1 :

1 mg

price1 :

350 USD

more info or order :

MyBioSource product webpage