catalog number :
MBS310614
products full name :
MAb to PTH (a.a. 53-68)
products short name :
Parathyroid Hormone (a.a. 53-68) (PTH)
products name syn :
Monoclonal Antibody to Human Parathyroid Hormone (PTH), amino acids 53-68
other names :
parathyroid hormone; Parathyroid hormone; parathyroid hormone; parathyrin; Parathyrin
other gene names :
PTH; PTH; PTH
uniprot entry name :
PTHY_CANFA
host :
Host: Mouse. Source: Tissue Culture
specificity :
Parathyroid Hormone (a.a. 53-68) (PTH). Human PTH peptide (a.a. 53-68). Does not cross react with Synthetic human PTH peptide (a.a. 1-10, a.a. 1-34 and a.a. 1-38).
form :
Purified, Lyophilized. Reconstitute in 10ul double distilled water.
storage stability :
Store lyophilized product at 2 to 8 degree C. After reconstitution, store at -20 degree C. Avoid multiple freeze/thaw cycles.
tested application :
EIA/ELISA, Immunohistochemistry
other info1 :
Immunogen: Synthetic human PTH peptide (53-84) bTG-conjugated. Affinity Constant: >2 x 10^10 l/mol
other info2 :
Buffer: Lyophilized from 0.1M PBS, pH 7.4. Preservative: No. Lyophilized: Yes. Important Note: Vial Contains Small Quantity. Centrifuge Product Before Opening!
products categories :
Monoclonal Antibodies to Hormones and Steroids
products references :
Kyriatsoulis, A., et al., (1998), "ELECSYS PTH, Parathyroid Hormone: A rapid and sensitive Immunoassay using fully automatic Electrochemiluminescence for Bone Metabolism Assessment", Osteoporosis International 8 (Suppl. 3), 81.
ncbi acc num :
NP_001003302.1
ncbi gb acc num :
NM_001003302.1
ncbi mol weight :
12,957 Da
ncbi pathways :
Class B/2 (Secretin Family Receptors) Pathway (364239); G Alpha (s) Signalling Events Pathway (364244); GPCR Downstream Signaling Pathway (364243); GPCR Ligand Binding Pathway (364216); Signaling By GPCR Pathway (364215)
uniprot summary :
Function: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. Subunit structure: Interacts with PTH1R (via N-terminal extracellular domain). Subcellular location: Secreted. Sequence similarities: Belongs to the parathyroid hormone family.