protein

Recombinant Human CD138 Protein

MBS306517

0.01 mg

425 USD

Recombinant Protein

Recombinant Human CD138 Protein

CD138

syndecan-1; Syndecan-1; syndecan-1; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; syndecan proteoglycan 1; syndecan 1; CD_antigen: CD138

CD138

SDC1; SDC1; SDC; CD138; SYND1; syndecan; SDC; SYND1

SDC1_HUMAN

310

Store at -20 degree to -80 degree C. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date. If unexpected results are observed which cannot be explained by variations in laboratory procedures and a problem with the reagent is suspected, contact Technical Support.

Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 32kDa. Syndecan-1 also exhibits molecular polymorphism with its core protein about 73kDa and its isoforms up to 400kDa. Source: Recombinant protein encoding human CD138 aa 18-218 expressed in E Coli.

Domain: aa 18-218

29568086

NP_002988.3

NM_002997

32,462 Da

A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (645305); Arf6 Trafficking Events Pathway (137954); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Chylomicron-mediated Lipid Transport Pathway (106157); Defective B3GAT3 Causes JDSSDHD Pathway (1127588); Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway (1127592); Defective B4GALT7 Causes EDS, Progeroid Type Pathway (1127587); Defective CHST14 Causes EDS, Musculocontractural Type Pathway (1127591)

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]

syndecan-1: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Belongs to the syndecan proteoglycan family. Protein type: Membrane protein, integral; Extracellular matrix; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 2p24.1. Cellular Component: lysosomal lumen; protein complex; focal adhesion; cell surface; Golgi lumen; integral to plasma membrane; cytoplasm; plasma membrane; external side of plasma membrane. Molecular Function: protein C-terminus binding; protein binding; glycoprotein binding. Biological Process: phototransduction, visible light; extracellular matrix organization and biogenesis; myoblast development; response to cAMP; glycosaminoglycan metabolic process; wound healing; striated muscle cell development; response to toxin; response to glucocorticoid stimulus; lipoprotein metabolic process; pathogenesis; Wnt receptor signaling pathway through beta-catenin; Sertoli cell development; odontogenesis; chondroitin sulfate metabolic process; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; response to hydrogen peroxide; ureteric bud development; carbohydrate metabolic process; response to calcium ion; retinoid metabolic process; inflammatory response

0.01 mg

425 USD