This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human FHIT Protein
catalog :
MBS306032
quantity :
0.01 mg
price :
425 USD
product information
catalog number :
MBS306032
products type :
Recombinant Protein
products full name :
Recombinant Human FHIT Protein
products short name :
FHIT
other names :
FHIT, partial; Diadenosine triphosphate hydrolase; Diadenosine triphosphate hydrolase
products gene name :
FHIT
other gene names :
FHIT
uniprot entry name :
Q71VB2_HUMAN
sequence length :
34
storage stability :
Store at -20 degree to -80 degree C. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date. If unexpected results are observed which cannot be explained by variations in laboratory procedures and a problem with the reagent is suspected, contact Technical Support.
other info1 :
Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 43kDa. Source: Recombinant full length human FHIT protein expressed in E Coli.
other info2 :
Domain: full length
ncbi gi num :
122056451
ncbi acc num :
ABM66092.1
ncbi mol weight :
3,844 Da
ncbi summary :
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
uniprot summary :
FHIT: a member of the histidine triad gene family. A diadenosine 5 ,5 -P1,P3-triphosphate hydrolase involved in purine metabolism. Its gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. A possible tumor suppressor in specific tissues. Phospho-FHIT observed in liver and kidney, but not in brain and lung. Phospho-FHIT undetected in all tested human tumor cell lines. Aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Protein type: Hydrolase; Motility/polarity/chemotaxis; EC 3.6.1.29; Tumor suppressor; DNA replication; Nucleotide Metabolism - purine. Chromosomal Location of Human Ortholog: 3p14.2. Cellular Component: mitochondrion; cytoplasm; cytosol; nucleus. Molecular Function: identical protein binding; protein binding; hydrolase activity; ubiquitin protein ligase binding; bis(5 -adenosyl)-triphosphatase activity; nucleotide binding; catalytic activity. Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleotide metabolic process; DNA replication; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; purine nucleotide metabolic process
size1 :
0.01 mg
price1 :
425 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!