product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Anti-Human Tubulin-gamma Polyclonal Antibody
catalog :
MBS301666
quantity :
0.1 ml
price :
170 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, rat, dog, mouse
application :
immunohistochemistry - paraffin section, immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS301666
products type :
Antibody
products full name :
Rabbit Anti-Human Tubulin-gamma Polyclonal Antibody
products short name :
Tubulin-gamma
other names :
tubulin gamma-1 chain; Tubulin gamma-1 chain; tubulin gamma-1 chain; gamma-tubulin complex component 1; tubulin, gamma polypeptide; tubulin, gamma 1; Gamma-1-tubulin; Gamma-tubulin complex component 1; GCP-1
other gene names :
TUBG1; TUBG1; TUBG; GCP-1; CDCBM4; TUBGCP1; TUBG; GCP-1
uniprot entry name :
TBG1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human. Predicted Reactivity: Bovine, Dog, Frog, Mouse, Rat
sequence length :
451
form :
0.1 ml immunogen affinity purified rabbit polyclonal antibody in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
storage stability :
Store at 2-8 degree C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date. There are no definitive signs to indicate instability of this product; therefore, positive and negative controls should be tested simultaneously with unknown specimens. If unexpected results are observed which cannot be explained by variations in laboratory procedures and a problem with the reagent is suspected, contact Technical Support.
tested application :
Immunohistochemistry (IHC) Paraffin
app notes :
Immunohistochemistry Procedure . Specimen Preparation: Formalin-fixed, paraffin-embedded tissues are suitable for use with this primary antibody. Deparaffinization: Deparaffinize slides using xylene or xylene alternative and graded alcohols. Antibody Dilution: If using the concentrate format of this product, dilute the antibody 1:100. The dilutions are estimates; actual results may differ because of variability in methods and protocols. Antigen Retrieval: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Primary Antibody Incubation: Incubate for 30 minutes at RT. Slide Washing: Slides must be washed in between steps. Rinse slides with PBS/0.05% Tween. Visualization: Detect the antibody as instructed by the instructions provided with the visualization system. Immunohistochemistry Dilution: 1:100. IHC Positive Control: Colon Carcinoma
other info2 :
Immunogen: Synthetic peptide derived from C-terminus of human tubulin gamma protein. Control Tissue: Colon Carcinoma. Cellular Localization: Cytoplasm. Entrez Gene Code: 7283. Pathway: Cytoskeletal Proteins
products description :
Tubulin gamma, an essential structural protein for cell growth, organizes microtubule arrays in the nucleus and cytoplasm. Tubulin gamma-depleted cells fail to form functional spindles and arrest during nuclear division. Tubulin gamma associates with spindle body components Spc97 and Spc98 to form the tubulin gamma complex. The phosphorylation of tubulin gamma at Tyr445 plays a regulatory role in microtubule formation. The incidence rate for this phosphorylation event peaks during G1.
ncbi gi num :
31543831
ncbi acc num :
NP_001061.2
ncbi gb acc num :
NM_001070.4
ncbi mol weight :
50 kDa
ncbi pathways :
Anchoring Of The Basal Body To The Plasma Membrane Pathway 1127503!!Assembly Of The Primary Cilium Pathway 1127502!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Centrosome Maturation Pathway 105807!!G2/M Transition Pathway 105801!!Loss Of Nlp From Mitotic Centrosomes Pathway 105811!!Loss Of Proteins Required For Interphase Microtubule Organizationfrom The Centrosome Pathway 105810!!Mitotic G2-G2/M Phases Pathway 160942!!Organelle Biogenesis And Maintenance Pathway 1127494
ncbi summary :
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009]
size :
0.1 ml
price :
170 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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