catalog number :
MBS301271
products full name :
Rabbit Anti-Human Gastrin 1 Polyclonal Antibody
products short name :
Gastrin-1
other names :
gastrin preproprotein; Gastrin; gastrin; preprogastrin; gastrin; Gastrin component I
products gene name :
Gastrin-1
other gene names :
GAST; GAST; GAS; GAS; G52; G34; G17; G14; G6
uniprot entry name :
GAST_HUMAN
reactivity :
Human. Predicted Reactivity: Bovine, Dog, Mouse, Pig, Rabbit, Rat
form :
0.1 ml immunogen affinity purified rabbit polyclonal antibody in PBS/1% BSA buffer pH 7.6 with less than 0.1%sodium azide.
storage stability :
Store at 2-8 degree C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date. There are no definitive signs to indicate instability of this product; therefore, positive and negative controls should be tested simultaneously with unknown specimens. If unexpected results are observed which cannot be explained by variations in laboratory procedures and a problem with the reagent is suspected, contact Technical Support.
tested application :
Immunohistochemistry (IHC) Paraffin
app notes :
Immunohistochemistry Procedure . Specimen Preparation: Formalin-fixed, paraffin-embedded tissues are suitable for use with this primary antibody. Deparaffinization: Deparaffinize slides using xylene or xylene alternative and graded alcohols. Antibody Dilution: If using the concentrate format of this product, dilute the antibody 1:200. The dilutions are estimates; actual results may differ because of variability in methods and protocols. Antigen Retrieval: None Primary Antibody Incubation: Incubate for 10 minutes at Room Temperature. Slide Washing: Slides must be washed in between steps. Rinse slides with PBS/0.05% Tween. Visualization: Detect the antibody as instructed by the instructions provided with the visualization system. Immunohistochemistry Dilution: 1:200. IHC Positive Control: Stomach
other info2 :
Immunogen: Synthetic peptide derived from N-terminus of gastrin-1. Control Tissue: Stomach. Cellular Localization: Cytoplasm. Entrez Gene Code: 2520. Pathway: Hormones
products description :
Gastrin is a 17 amino acid peptide hormone and neurotransmitter widely distributed throughout the Gastrin is a 17 amino acid peptide hormone and neurotransmitter widely distributed throughout the with gastrin may be used to study the differential tissue expression and intracellular and subcellular localization of gastrin in neuroendocrine cells of the gastrointestinal tract, and in the CNS.
ncbi acc num :
NP_000796.1
ncbi gb acc num :
NM_000805.4
ncbi pathways :
G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); Gastric Acid Secretion Pathway (154409); Gastric Acid Secretion Pathway (154383); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
ncbi summary :
Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq, Jul 2008]
uniprot summary :
gastrin: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. Belongs to the gastrin/cholecystokinin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 17q21. Cellular Component: extracellular region. Molecular Function: protein binding; hormone activity. Biological Process: G-protein coupled receptor protein signaling pathway; signal transduction
size1 :
0.1 mL (Concentrate)
size3 :
0.5 mL (Concentrate)
size4 :
1 mL (Concentrate)