product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Anti-Human Actin-Skeletal Muscle Polyclonal Antibody
catalog :
MBS300923
quantity :
0.1 ml
price :
155 USD
clonality :
polyclonal
host :
rabbit
reactivity :
chicken, rat, human, mouse
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS300923
products type :
Antibody
products full name :
Rabbit Anti-Human Actin-Skeletal Muscle Polyclonal Antibody
products short name :
Actin-Skeletal Muscle
other names :
actin, alpha skeletal muscle; Actin, alpha skeletal muscle; actin, alpha skeletal muscle; nemaline myopathy type 3; actin, alpha 1, skeletal muscle; Alpha-actin-1
other gene names :
ACTA1; ACTA1; ACTA; ASMA; CFTD; MPFD; NEM1; NEM2; NEM3; CFTD1; CFTDM; ACTA
uniprot entry name :
ACTS_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human. Predicted Reactivity: Bovine, Chicken, Frog, Mouse, Pig, Rabbit, Rat
sequence length :
377
form :
0.1 ml immunogen affinity purified rabbit polyclonal antibody in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
storage stability :
Store at 2-8 degree C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date. There are no definitive signs to indicate instability of this product; therefore, positive and negative controls should be tested simultaneously with unknown specimens. If unexpected results are observed which cannot be explained by variations in laboratory procedures and a problem with the reagent is suspected, contact Technical Support.
tested application :
Immunohistochemistry (IHC) Paraffin
app notes :
Immunohistochemistry Procedure . Specimen Preparation: Formalin-fixed, paraffin-embedded tissues are suitable for use with this primary antibody. Deparaffinization: Deparaffinize slides using xylene or xylene alternative and graded alcohols. Antibody Dilution: If using the concentrate format of this product, dilute the antibody 1:200. The dilutions are estimates; actual results may differ because of variability in methods and protocols. Antigen Retrieval: No special pretreatment necessary. Antigen Retrieval: No special pretreatment necessary. Slide Washing: Slides must be washed in between steps. Rinse slides with PBS/0.05% Tween. Visualization: Detect the antibody as instructed by the instructions provided with the visualization Visualization: Detect the antibody as instructed by the instructions provided with the visualization. Immunohistochemistry Dilution: 1:200. IHC Positive Control: Skeletal Muscle
other info2 :
Immunogen: Synthetic peptide derived from N-terminus of human alpha skeletal muscle isoform of actin. Control Tissue: Skeletal Muscle. Cellular Localization: Cytoplasm. Entrez Gene Code: 58. Pathway: Muscle Markers
products description :
This antibody reacts with sarcomeric actins of normal tissues and neoplasms derived from such tissues (i.e. rhabdomyosarcomas).
ncbi gi num :
4501881
ncbi acc num :
NP_001091.1
ncbi gb acc num :
NM_001100.3
ncbi mol weight :
42 kDa
ncbi pathways :
Caspase Cascade In Apoptosis Pathway 137974!!Hypothetical Network For Drug Addiction Pathway 198776!!Myometrial Relaxation And Contraction Pathways 198759!!RhoA Signaling Pathway 169356!!Signaling Events Mediated By Focal Adhesion Kinase Pathway 169348!!Striated Muscle Contraction Pathway 198903
ncbi summary :
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]
size :
0.1 ml
price :
155 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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