product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Anti-Human p120 (Catenin delta 1) Polyclonal Antibody
catalog :
MBS300881
quantity :
1 ml
price :
485 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse
application :
immunohistochemistry - paraffin section, immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS300881
products type :
Antibody
products full name :
Rabbit Anti-Human p120 (Catenin delta 1) Polyclonal Antibody
products short name :
p120
other names :
catenin delta-1 isoform 1ABC; Catenin delta-1; catenin delta-1; cadherin-associated Src substrate; p120 catenin; catenin (cadherin-associated protein), delta 1; Cadherin-associated Src substrate; CAS; p120 catenin; p120(ctn); p120(cas)
products gene name :
p120
other gene names :
CTNND1; CTNND1; CAS; p120; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN); KIAA0384; CAS; p120(ctn)
uniprot entry name :
CTND1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human. Predicted Reactivity: Mouse
sequence length :
968
form :
1.0 ml immunogen affinity purified rabbit polyclonal antibody in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
storage stability :
Store at 2-8 degree C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date. There are no definitive signs to indicate instability of this product; therefore, positive and negative controls should be tested simultaneously with unknown specimens. If unexpected results are observed which cannot be explained by variations in laboratory procedures and a problem with the reagent is suspected, contact Technical Support.
tested application :
Immunohistochemistry (IHC) Paraffin
app notes :
Immunohistochemistry Procedure . Specimen Preparation: Formalin-fixed, paraffin-embedded tissues are suitable for use with this primary antibody. Deparaffinization: Deparaffinize slides using xylene or xylene alternative and graded alcohols. Antibody Dilution: If using the concentrate format of this product, dilute the antibody 1:100. The dilutions are estimates; actual results may differ because of variability in methods and protocols. Antigen Retrieval: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min. Primary Antibody Incubation: Incubate for 30 minutes at room temperature. Slide Washing: Slides must be washed in between steps. Rinse slides with PBS/0.05% Tween. Visualization: Detect the antibody as instructed by the instructions provided with the visualization system. Immunohistochemistry Dilution: 1:100. IHC Positive Control: Breast Lobular Carcinoma
other info2 :
Immunogen: Synthetic peptide corresponding to C-terminus of human p120. Control Tissue: Breast Carcinoma. Cellular Localization: Cytoplasm, Membrane. Entrez Gene Code: 1500. Pathway: Cell Adhesion
products description :
Catenin delta (p120) is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.
ncbi gi num :
146231940
ncbi acc num :
NP_001078927.1
ncbi gb acc num :
NM_001085458.1
ncbi mol weight :
108 kDa
ncbi pathways :
Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Adherens Junctions Interactions Pathway 119533!!Arf6 Trafficking Events Pathway 137954!!Cell Junction Organization Pathway 160966!!Cell-Cell Communication Pathway 477132!!Cell-cell Junction Organization Pathway 119532!!E-cadherin Signaling In Keratinocytes Pathway 138002!!E-cadherin Signaling In The Nascent Adherens Junction Pathway 138005!!EGFR1 Signaling Pathway 198782
ncbi summary :
This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010]
size :
1 ml
price :
485 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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