This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Anti-Human Fli-1 Polyclonal Antibody
catalog :
MBS300723
quantity :
1 ml
price :
410 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
immunohistochemistry, immunohistochemistry - paraffin section
citations: 2
Reference
Gierisch M, Pedot G, Walser F, Lopez Garcia L, Jaaks P, Niggli F, et al. USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth. Sci Rep. 2019;9:951 pubmed publisher
Schwentner R, Papamarkou T, Kauer M, Stathopoulos V, Yang F, Bilke S, et al. EWS-FLI1 employs an E2F switch to drive target gene expression. Nucleic Acids Res. 2015;43:2780-9 pubmed publisher
product information
catalog number :
MBS300723
products type :
Antibody
products full name :
Rabbit Anti-Human Fli-1 Polyclonal Antibody
products short name :
FLI-1
other names :
Friend leukemia integration 1 transcription factor isoform 2; Friend leukemia integration 1 transcription factor; Friend leukemia integration 1 transcription factor; Ewing sarcoma breakpoint region 2; Friend leukemia virus integration 1; transcription factor ERGB; Fli-1 proto-oncogene, ETS transcription factor; Proto-oncogene Fli-1; Transcription factor ERGB
products gene name :
FLI-1
other gene names :
FLI1; FLI1; EWSR2; SIC-1
uniprot entry name :
FLI1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human. Predicted Reactivity: Bovine, Dog, Frog, Mouse, Rabbit, Rat
sequence length :
419
form :
1.0 ml immunogen affinity purified rabbit polyclonal antibody in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
storage stability :
Store at 2-8 degree C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date. There are no definitive signs to indicate instability of this product; therefore, positive and negative controls should be tested simultaneously with unknown specimens. If unexpected results are observed which cannot be explained by variations in laboratory procedures and a problem with the reagent is suspected, contact Technical Support.
tested application :
Immunohistochemistry (IHC) Paraffin
app notes :
Immunohistochemistry Procedure . (1) Specimen Preparation: Formalin-fixed, paraffin-embedded tissues are suitable for use with this primary antibody. Deparaffinization: Deparaffinize slides using xylene or xylene alternative and graded alcohols. (2) Antibody Dilution: If using the concentrate format of this product, dilute the antibody 1:50. The dilutions are estimates; actual results may differ because of variability in methods and protocols. (3) Antigen Retrieval: Boil tissue section in 10mM Citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min. Primary Antibody Incubation: Incubate for 30 minutes at room temperature. (4) Slide Washing: Slides must be washed in between steps. Rinse slides with PBS/0.05% Tween. (5) Visualization: Detect the antibody as instructed by the instructions provided with the visualization system. Immunohistochemistry Dilution: 1:50. IHC Positive Control: Angiosarcoma, Ewing's Sarcoma, Placenta
other info2 :
Immunogen: Synthetic peptide derived from C-terminus of human FLI-1. Control Tissue: Angiosarcoma, Ewing's Sarcoma, Placenta. Cellular Localization: Nucleus. Entrez Gene Code: 2313. Pathway: Cancer Markers
products description :
Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets- 1, Ets-2, Erg-1, Erg-2, Elk, E74, Fli-1, PU.1 and PEA3. Members of the Ets gene family exhibit varied pattern of tissue expression, and share a highly conserved carboxy terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence.
ncbi gi num :
264681554
ncbi acc num :
NP_001161153.1
ncbi gb acc num :
NM_001167681.2
ncbi mol weight :
~50 kDa
ncbi pathways :
Transcriptional Misregulation In Cancer Pathway 523016!!Transcriptional Misregulation In Cancer Pathway 522987
size1 :
1 ml
price1 :
410 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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