catalog number :
MBS300286
products full name :
Rabbit Anti-Human Jena-Muenchen 4 (JM4) Polyclonal Antibody
products short name :
Jena-Muenchen4
other names :
PRA1 family protein 2; PRA1 family protein 2; PRA1 family protein 2; Jena-Muenchen 4; PRA1 domain family, member 2
other gene names :
PRAF2; PRAF2; JM4
uniprot entry name :
PRAF2_HUMAN
reactivity :
Human. Predicted Reactivity: Bovine, Dog, Mouse, Rabbit
form :
1.0 ml immunogen affinity purified rabbit polyclonal antibody in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
storage stability :
Store at 2-8 degree C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date. There are no definitive signs to indicate instability of this product; therefore, positive and negative controls should be tested simultaneously with unknown specimens. If unexpected results are observed which cannot be explained by variations in laboratory procedures and a problem with the reagent is suspected, contact Technical Support.
tested application :
Immunohistochemistry (IHC) Paraffin
app notes :
Immunohistochemistry Procedure . Specimen Preparation: Formalin-fixed, paraffin-embedded tissues are suitable for use with this primary antibody. Deparaffinization: Deparaffinize slides using xylene or xylene alternative and graded alcohols. Antibody Dilution: If using the concentrate format of this product, dilute the antibody 1:100. The dilutions are estimates; actual results may differ because of variability in methods and protocols. Antigen Retrieval: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min. Primary Antibody Incubation: Incubate for 30 minutes at room temperature. Slide Washing: Slides must be washed in between steps. Rinse slides with PBS/0.05% Tween. Visualization: Detect the antibody as instructed by the instructions provided with the visualization system. Immunohistochemistry Dilution: 1:100. IHC Positive Control: Brain
other info2 :
Immunogen: Synthetic peptide corresponding to aa 165-178 of human JM4. Control Tissue: Brain. Cellular Localization: Cytoplasm, Membrane. Entrez Gene Code: 11230. Pathway: Signal Transduction
products description :
JM4 is a 19kDa four-transmembrane protein binding to the CCR5 receptor. It plays a role in the regulation of intracellular protein transport. It is expressed in normal brain, small intestine, lung, spleen, and pancreas and has also been detected in tumors of breast, colon, lung, and ovary.
ncbi acc num :
NP_009144.1
ncbi gb acc num :
NM_007213.2