Mouse Anti-Human GLUT-1 Monoclonal Antibody (Clone SPM498) | MyBioSource MBS300259 product information

product summary

request information :

company name :

MyBioSource

product type :

antibody

product name :

Mouse Anti-Human GLUT-1 Monoclonal Antibody (Clone SPM498)

catalog :

MBS300259

quantity :

1 ml

price :

485 USD

clonality :

monoclonal

host :

mouse

reactivity :

human

application :

immunohistochemistry - paraffin section, immunohistochemistry

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS300259

products type :

Antibody

products full name :

Mouse Anti-Human GLUT-1 Monoclonal Antibody (Clone SPM498)

products short name :

GLUT-1

other names :

solute carrier family 2, facilitated glucose transporter member 1; Solute carrier family 2, facilitated glucose transporter member 1; solute carrier family 2, facilitated glucose transporter member 1; glucose transporter type 1, erythrocyte/brain; hepG2 glucose transporter; human T-cell leukemia virus (I and II) receptor; receptor for HTLV-1 and HTLV-2; solute carrier family 2 (facilitated glucose transporter), member 1; Glucose transporter type 1, erythrocyte/brain; GLUT-1; HepG2 glucose transporter

products gene name :

GLUT-1

other gene names :

SLC2A1; SLC2A1; PED; DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT-1; GLUT1DS; GLUT1; GLUT-1

uniprot entry name :

GTR1_HUMAN

clonality :

Monoclonal

isotype :

IgG2a/k

clone :

SPM498

host :

Mouse

reactivity :

Human

sequence length :

492

form :

1.0 ml mouse monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

storage stability :

Store at 2-8 degree C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date. There are no definitive signs to indicate instability of this product; therefore, positive and negative controls should be tested simultaneously with unknown specimens. If unexpected results are observed which cannot be explained by variations in laboratory procedures and a problem with the reagent is suspected, contact Technical Support.

tested application :

Immunohistochemistry (IHC) Paraffin

app notes :

Immunohistochemistry Procedure . Specimen Preparation: Formalin-fixed, paraffin-embedded tissues are suitable for use with this primary antibody. Deparaffinization: Deparaffinize slides using xylene or xylene alternative and graded alcohols. Antibody Dilution: If using the concentrate format of this product, dilute the antibody 1:200. The dilutions are estimates; actual results may differ because of variability in methods and protocols. Antigen Retrieval: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min. Primary Antibody Incubation: Incubate for 30 minutes at room temperature. Slide Washing: Slides must be washed in between steps. Rinse slides with PBS/0.05% Tween. Visualization: Detect the antibody as instructed by the instructions provided with the visualization system. Immunohistochemistry Dilution: 1:200. IHC Positive Control: Esophageal Carcinoma, Breast Carcinoma

other info2 :

Immunogen: Synthetic peptide derived from C-terminus of human GLUT-1 protein. Control Tissue: Breast Carcinoma, Esophagus. Cellular Localization: Membrane. Entrez Gene Code: 6513. Pathway: Neuroscience

products description :

Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF-1 induced signaling. GLUT-1 is detectable in many human tissues including those of the colon, lung, stomach, esophagus, and breast.

ncbi gi num :

166795299

ncbi acc num :

NP_006507.2

ncbi gb acc num :

NM_006516.2

ncbi mol weight :

55 kDa

ncbi pathways :

Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Bile Secretion Pathway 193146!!Bile Secretion Pathway 193095!!Central Carbon Metabolism In Cancer Pathway 1059538!!Central Carbon Metabolism In Cancer Pathway 1084231!!Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway 906000!!Defective BTD Causes Biotidinase Deficiency Pathway 906015!!Defective CD320 Causes Methylmalonic Aciduria Pathway 906012!!Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway 906001

ncbi summary :

This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Apr 2013]

size :

1 ml

price :

485 USD

more info or order :

MyBioSource product webpage