catalog number :
MBS300121
products full name :
Mouse Anti-Human Mucin 5AC Monoclonal Antibody (Clone 45M1)
products short name :
Mucin 5AC
other names :
PREDICTED: mucin-5AC; Mucin-5AC; mucin-5AC; gastric mucin; lewis B blood group antigen; major airway glycoprotein; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin 5AC, oligomeric mucus/gel-forming pseudogene; mucin-5 subtype AC, tracheobronchial; tracheobronchial mucin; mucin 5AC, oligomeric mucus/gel-forming; Gastric mucin; Lewis B blood group antigen; LeB; Major airway glycoprotein; Mucin-5 subtype AC, tracheobronchial; Tracheobronchial mucin; TBM
other gene names :
MUC5AC; MUC5AC; TBM; leB; MUC5; MUC5; MUC-5AC; LeB; TBM
uniprot entry name :
MUC5A_HUMAN
form :
1.0 ml mouse monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
storage stability :
Store at 2-8 degree C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date. There are no definitive signs to indicate instability of this product; therefore, positive and negative controls should be tested simultaneously with unknown specimens. If unexpected results are observed which cannot be explained by variations in laboratory procedures and a problem with the reagent is suspected, contact Technical Support.
tested application :
Immunohistochemistry (IHC) Paraffin
app notes :
Immunohistochemistry Procedure . Specimen Preparation: Formalin-fixed, paraffin-embedded tissues are suitable for use with this primary antibody. Deparaffinization: Deparaffinize slides using xylene or xylene alternative and graded alcohols. Antibody Dilution: If using the concentrate format of this product, dilute the antibody 1:100. The dilutions are estimates; actual results may differ because of variability in methods and protocols. Antigen Retrieval: None Primary Antibody Incubation: Incubate for 30 minutes at room temperature. Slide Washing: Slides must be washed in between steps. Rinse slides with PBS/0.05% Tween. Visualization: Detect the antibody as instructed by the instructions provided with the visualization system. Immunohistochemistry Dilution: 1:100. IHC Positive Control: Stomach
other info2 :
Immunogen: M1 mucin preparation from the fluid of an ovarian mucinous cyst. Control Tissue: Stomach. Cellular Localization: Cytoplasm, Membrane. Entrez Gene Code: 4586. Pathway: Cancer Markers
products description :
Mucins are high molecular eight glycoproteins with 80% carbohydrate contents and the remaining 20% is constituted by protein core. Gastric mucin is found in normal human gastrointestinal tract. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
ncbi acc num :
XP_003119529.1
ncbi gb acc num :
XM_003119481.1
ncbi mol weight :
>1000 kDa
ncbi pathways :
Metabolism Of Proteins Pathway 106230!!O-linked Glycosylation Pathway 1127679!!O-linked Glycosylation Of Mucins Pathway 530747!!Post-translational Protein Modification Pathway 161012!!Termination Of O-glycan Biosynthesis Pathway 530748