catalog number :
MBS2888945
products type :
Recombinant Protein
products full name :
Beta-1 adrenergic receptor
products short name :
[Beta-1 adrenergic receptor]
products name syn :
[ADRB1R; B1AR; Beta-1 adrenoreceptor; Beta-1 adrenoceptor]
other names :
[beta-1 adrenergic receptor; Beta-1 adrenergic receptor; beta-1 adrenergic receptor; adrenoceptor beta 1; Beta-1 adrenoreceptor; Beta-1 adrenoceptor]
products gene name :
[ADRB1]
other gene names :
[ADRB1; ADRB1; RHR; B1AR; ADRB1R; BETA1AR; ADRB1R; B1AR; Beta-1 adrenoceptor]
sequence :
CRSPDFRKAFQLLCCARRAARRRHATHGDRPRASGCLAR
RPGPPPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGA
AADSDSSLDEPCRPGFASESKV
specificity :
0.5 mg/mL x 0.2mL
storage stability :
Store at -20°C for 6 months. Avoid repeated freezing and thawing.
tested application :
AP, Array, ELISA, WB.
image1 heading :
Testing Data(TD)
other info1 :
Organism: Homo sapiens (human)
other info2 :
Buffer: 50mM NaH 2 PO 4 , 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
products categories :
Cardiovascular
products description :
Recombinant protein with His-tag.
ncbi acc num :
NP_000675.1
ncbi gb acc num :
NM_000684.2
uniprot acc num :
P08588(378-477aa)
ncbi pathways :
Adrenoceptors Pathway (106365); Amine Ligand-binding Receptors Pathway (106363); Calcium Regulation In The Cardiac Cell Pathway (198906); Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285); Endocytosis Pathway (102279); Endocytosis Pathway (102181)
ncbi summary :
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008]
uniprot summary :
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling.