Human Aspartoacylase ELISA Kit | MyBioSource MBS288790 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Aspartoacylase ELISA Kit

catalog :

MBS288790

quantity :

48-Strip-Wells

price :

355 USD

product information

catalog number :

MBS288790

products type :

ELISA Kit

products full name :

Human Aspartoacylase ELISA Kit

products short name :

[Aspartoacylase]

products name syn :

[Aspartoacylase; Aminoacylase-2; ACY-2; ASPA; ACY2; ASP; 3.5.1.15]

other names :

[aspartoacylase; Aspartoacylase; aspartoacylase; aspartoacylase; Aminoacylase-2; ACY-2]

products gene name :

[ASPA]

other gene names :

[ASPA; ASPA; ASP; ACY2; ACY2; ASP; ACY-2]

uniprot entry name :

ACY2_HUMAN

reactivity :

Human

sequence length :

313

specificity :

Recombinant and natural Human Tyrosine-protein kinase CSK

storage stability :

For long term storage, please store the entire kit at -20 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Tissue Homogenates, Cell Culture Supernates Or Other Biological Fluids. Detection Range: 0.78-50 ng/mL. Sensitivity: <0.43 ng/mL

other info2 :

Intra-assay Precision: Intra-Assay CV: <=5.5%. Inter-assay Precision: Inter-Assay CV: <=10.1%

products description :

Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

4557335

ncbi acc num :

NP_000040.1

ncbi gb acc num :

NM_000049.2

uniprot acc num :

P45381

ncbi mol weight :

35,735 Da

ncbi pathways :

Alanine And Aspartate Metabolism Pathway (198783); Alanine, Aspartate And Glutamate Metabolism Pathway (101142); Alanine, Aspartate And Glutamate Metabolism Pathway (100063); Amino Acid Synthesis And Interconversion (transamination) Pathway (1270159); Histidine Metabolism Pathway (82958); Histidine Metabolism Pathway (324); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Amino Acids And Derivatives Pathway (1270158)

ncbi summary :

This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

ASPA: Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids. Defects in ASPA are the cause of Canavan disease (CAND); also known as spongy degeneration of the brain. CAND is a rare neurodegenerative condition of infancy or childhood characterized by white matter vacuolization and demeylination that gives rise to a spongy appearance. The clinical features are onset in early infancy, atonia of neck muscles, hypotonia, hyperextension of legs and flexion of arms, blindness, severe mental defect, megalocephaly, and death by 18 months on the average. Belongs to the AspA/AstE family. Aspartoacylase subfamily. Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; Hydrolase; Amino Acid Metabolism - histidine; EC 3.5.1.15. Chromosomal Location of Human Ortholog: 17p13.3. Cellular Component: cytoplasm; cytosol; nucleus. Molecular Function: aminoacylase activity; aspartoacylase activity; hydrolase activity, acting on ester bonds; metal ion binding; protein binding. Biological Process: amino acid biosynthetic process; aspartate catabolic process. Disease: Canavan Disease

size1 :

48-Strip-Wells

price1 :

355 USD

size2 :

96-Strip-Wells

price2 :

475

size3 :

5x96-Strip-Wells

price3 :

2030

size4 :

10x96-Strip-Wells

price4 :

3700