catalog number :
MBS2886471
products type :
ELISA Kit
products full name :
Human Natural cytotoxicity triggering receptor 3 ligand 1 ELISA Kit
products short name :
[Natural cytotoxicity triggering receptor 3 ligand 1]
products name syn :
[B7 homolog 6; B7-H6; B7H6]
other names :
[natural cytotoxicity triggering receptor 3 ligand 1; Natural cytotoxicity triggering receptor 3 ligand 1; natural cytotoxicity triggering receptor 3 ligand 1; natural killer cell cytotoxicity receptor 3 ligand 1; B7 homolog 6; B7-H6]
products gene name :
[NCR3LG1]
other gene names :
[NCR3LG1; NCR3LG1; B7H6; B7-H6; DKFZp686O24166; B7H6; B7-H6]
uniprot entry name :
NR3L1_HUMAN
storage stability :
For long term storage, please store the entire kit at -20 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.
products description :
Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
ncbi acc num :
NP_001189368.1
ncbi gb acc num :
NM_001202439.2
ncbi mol weight :
50,827 Da
ncbi pathways :
Adaptive Immune System Pathway (1269171); Immune System Pathway (1269170); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (1269201)
ncbi summary :
B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]
uniprot summary :
B7-H6: Triggers NCR3-dependent natural killer cell activation. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 11p15.1. Cellular Component: integral to membrane; plasma membrane; viral capsid. Molecular Function: structural molecule activity. Biological Process: regulation of immune response
size4 :
10x96-Strip-Wells