ELISA/assay

Human Transient receptor potential cation channel subfamily V member 1 ELISA Kit

MBS2885974

48-Strip-Wells

355 USD

ELISA Kit

Human Transient receptor potential cation channel subfamily V member 1 ELISA Kit

[Transient receptor potential cation channel subfamily V member 1]

[Transient receptor potential cation channel subfamily V member 1; TrpV1; Capsaicin receptor; Osm-9-like TRP channel 1; OTRPC1; Vanilloid receptor 1; TRPV1; VR1]

[transient receptor potential cation channel subfamily V member 1; Transient receptor potential cation channel subfamily V member 1; transient receptor potential cation channel subfamily V member 1; transient receptor potential cation channel subfamily V member 1; Capsaicin receptor; Osm-9-like TRP channel 1; OTRPC1; Vanilloid receptor 1]

[TRPV1]

[TRPV1; TRPV1; VR1; VR1; TrpV1; OTRPC1]

TRPV1_HUMAN

Human

839

For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Samples: Serum, Plasma, Tissue Homogenates, Cell Culture Supernates Or Other Biological Fluids.

Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.

74315350

NP_061197.4

NM_018727.5

Q8NER1

94,211 Da

Inflammatory Mediator Regulation Of TRP Channels Pathway (948277); Inflammatory Mediator Regulation Of TRP Channels Pathway (948307); Ion Channel Transport Pathway (1269950); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Stimuli-sensing Channels Pathway (1269953); TRP Channels Pathway (1269954); Transmembrane Transport Of Small Molecules Pathway (1269903); Trk Receptor Signaling Mediated By PI3K And PLC-gamma Pathway (137967); Trk Receptor Signaling Mediated By The MAPK Pathway (138044)

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]

TRPV1: a receptor for capsaicin and a non-selective cation channel that is structurally related to members of the TRP family of ion channels. Activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Protein type: Channel, cation; Receptor, misc.; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 17p13.2. Cellular Component: cell junction; cell soma; cytosol; dendrite; external side of plasma membrane; integral to membrane; integral to plasma membrane; intrinsic to plasma membrane; plasma membrane; postsynaptic membrane. Molecular Function: ATP binding; calcium channel activity; calcium-release channel activity; calmodulin binding; chloride channel regulator activity; excitatory extracellular ligand-gated ion channel activity; identical protein binding; phosphoprotein binding; transmembrane receptor activity. Biological Process: behavioral response to pain; cell surface receptor linked signal transduction; chemosensory behavior; detection of chemical stimulus involved in sensory perception of pain; detection of temperature stimulus involved in sensory perception of pain; diet induced thermogenesis; elevation of cytosolic calcium ion concentration; fever; glutamate secretion; lipid metabolic process; microglial cell activation; peptide secretion; positive regulation of apoptosis; positive regulation of nitric oxide biosynthetic process; response to heat; response to peptide hormone stimulus; response to pH; sensory perception of mechanical stimulus; smooth muscle contraction involved in micturition; thermoception; transmembrane transport; transport

48-Strip-Wells

355 USD

96-Strip-Wells

475

5x96-Strip-Wells

2030

10x96-Strip-Wells

3700