catalog number :
MBS2885722
products type :
ELISA Kit
products full name :
Rat Interleukin-6 receptor subunit alpha ELISA Kit
products short name :
[Interleukin-6 receptor subunit alpha]
products name syn :
[Interleukin-6 receptor subunit alpha; IL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA; IL-6R 1; Il6r; Il6ra; CD126]
other names :
[Interleukin-6 receptor subunit alpha; Interleukin-6 receptor subunit alpha; interleukin-6 receptor subunit alpha; interleukin 6 receptor; IL-6R 1; CD_antigen: CD126]
products gene name :
[Il6r]
other gene names :
[Il6r; Il6r; IL6R1; Il6ra; Il6ra; IL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA]
uniprot entry name :
IL6RA_RAT
specificity :
Recombinant and natural Rat Interleukin-6 receptor subunit alpha,IL-6 receptor subunit alpha
storage stability :
For long term storage, please store the entire kit at -20 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Assay Type: Sandwich. Detection Range: 62.5-4000 pg/mL. Sensitivity: 31.32 pg/mL
other info2 :
Intra-Assay CV: <=5.2%. Inter-Assay CV: <=9.8%. Recovery: 97%
products description :
Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
ncbi mol weight :
50,401 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83443); Cytokine-cytokine Receptor Interaction Pathway (460); HIF-1 Signaling Pathway (695233); Hematopoietic Cell Lineage Pathway (83470); Hematopoietic Cell Lineage Pathway (489); IL-6 Signaling Pathway (198426); Jak-STAT Signaling Pathway (83469); Jak-STAT Signaling Pathway (488); Non-alcoholic Fatty Liver Disease (NAFLD) Pathway (862252); Non-alcoholic Fatty Liver Disease (NAFLD) Pathway (862314)
ncbi summary :
alpha subunit of the interleukin 6 receptor complex [RGD, Feb 2006]
uniprot summary :
Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
size4 :
10x96-Strip-Wells