ELISA/assay

Mouse Hepcidin ELISA Kit

MBS2885427

48-Strip-Wells

355 USD

ELISA Kit

Mouse Hepcidin ELISA Kit

[Hepcidin]

[Hepcidin; Hamp; Hamp1; Hepc; Hepc1]

[hepcidin; Hepcidin; hepcidin; hepcidin antimicrobial peptide]

[Hamp]

[Hamp; Hamp; Hepc; Hamp1; Hepc1; Hamp1; Hepc; Hepc1]

HEPC_MOUSE

Mouse

83

Recombinant and natural Mouse Hepcidin

For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Samples: Serum, Plasma, Tissue Homogenates, Cell Culture Supernates Or Other Biological Fluids.

Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.

14211542

NP_115930.1

NM_032541.1

Q9EQ21

9,352 Da

Iron Homeostasis Pathway (198312)

HAMP: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. Defects in HAMP are the cause of hemochromatosis type 2B (HFE2B); also known as juvenile hemochromatosis (JH). HFE2B is a disorder of iron metabolism with excess deposition of iron in the tissues, bronze skin pigmentation, hepatic cirrhosis, arthropathy and diabetes. The most common symptoms of hemochromatosis type 2 at presentation are hypogonadism and cardiomyopathy. Belongs to the hepcidin family. Protein type: Secreted, signal peptide; Secreted. Cellular Component: extracellular region; extracellular space; nucleus. Molecular Function: copper ion binding; hormone activity. Biological Process: cellular iron ion homeostasis; cellular response to extracellular stimulus; defense response to bacterium; defense response to fungus; iron ion homeostasis; JAK-STAT cascade; membrane protein proteolysis; myeloid cell homeostasis; negative regulation of bone resorption; negative regulation of inflammatory response; negative regulation of transcription from RNA polymerase II promoter; positive regulation of macrophage activation; positive regulation of transcription from RNA polymerase II promoter

48-Strip-Wells

355 USD

96-Strip-Wells

475

5x96-Strip-Wells

2030

10x96-Strip-Wells

3700