catalog number :
MBS2884645
products type :
ELISA Kit
products full name :
Mouse Corticoliberin ELISA Kit
products short name :
[Corticoliberin]
products name syn :
[Corticoliberin; Corticotropin-releasing factor; CRF; Corticotropin-releasing hormone; Crh; Gm1347]
other names :
[corticoliberin preproprotein; Corticoliberin; corticoliberin; corticotropin releasing hormone; Corticotropin-releasing factor; CRF; Corticotropin-releasing hormone]
products gene name :
[Crh]
other gene names :
[Crh; Crh; CRF; Gm1347; Gm1347; CRF]
uniprot entry name :
CRF_MOUSE
specificity :
Recombinant and natural Mouse Corticoliberin
storage stability :
For long term storage, please store the entire kit at -20 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Detection Range: 15.6 pg/mL -1000 pg/mL
other info2 :
Intra-assay Precision: Intra-Assay CV: <=5.2%. Inter-assay Precision: Inter-Assay CV: <=8.4%
ncbi acc num :
NP_991338.1
ncbi gb acc num :
NM_205769.3
ncbi mol weight :
20,778 Da
ncbi pathways :
Alcoholism Pathway (585577); Alcoholism Pathway (587116); Class B/2 (Secretin Family Receptors) Pathway (1324731); G Alpha (s) Signalling Events Pathway (1324736); GPCR Downstream Signaling Pathway (1324735); GPCR Ligand Binding Pathway (1324705); Long-term Depression Pathway (83283); Long-term Depression Pathway (497); Myometrial Relaxation And Contraction Pathways (198333); Serotonin And Anxiety Pathway (672436)
ncbi summary :
This gene encodes a member of the corticotropin-releasing factor family and preproprotein that is proteolytically processed to generate a mature protein product. This protein product is a neuropeptide hormone that binds to the corticotropin releasing hormone receptors (CRHR1 and CRHR2) to stimulate the release of adrenocorticotropic hormone from the pituitary gland in response to stress. The encoded protein may also regulate angiogenesis and inflammation. Homozygous knockout mice for this gene exhibit reduced corticosterone levels while the offspring of these mice die perinatally. [provided by RefSeq, Aug 2015]
uniprot summary :
CRH: This hormone from hypothalamus regulates the release of corticotropin from pituitary gland. Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family. Protein type: Secreted; Secreted, signal peptide. Cellular Component: cell soma; cytoplasm; extracellular region; extracellular space; perikaryon. Molecular Function: corticotropin-releasing hormone receptor 1 binding; corticotropin-releasing hormone receptor 2 binding; hormone activity. Biological Process: adrenal gland development; associative learning; female pregnancy; glucocorticoid biosynthetic process; induction of apoptosis by hormones; inflammatory response; learning and/or memory; lung development; negative regulation of blood pressure; negative regulation of epinephrine secretion; negative regulation of luteinizing hormone secretion; positive regulation of adrenocorticotropic hormone secretion; positive regulation of cAMP biosynthetic process; positive regulation of cell proliferation; positive regulation of cortisol secretion; positive regulation of protein amino acid phosphorylation; regulation of serotonin secretion; synaptic transmission, dopaminergic
size4 :
10x96-Strip-Wells