This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat Neutrophil gelatinase-associated lipocalin ELISA Kit
catalog :
MBS2884287
quantity :
48-Strip-Wells
price :
305 USD
product information
catalog number :
MBS2884287
products type :
ELISA Kit
products full name :
Rat Neutrophil gelatinase-associated lipocalin ELISA Kit
products short name :
[Neutrophil gelatinase-associated lipocalin]
products name syn :
[Neutrophil gelatinase-associated lipocalin; NGAL; Alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; Lipocalin-2; p25; Lcn2; p25]
other names :
[neutrophil gelatinase-associated lipocalin; Neutrophil gelatinase-associated lipocalin; neutrophil gelatinase-associated lipocalin; lipocalin 2; Alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; Lipocalin-2; Siderocalin LCN2; p25]
products gene name :
[Lcn2]
other gene names :
[Lcn2; Lcn2; Sip24; NGAL]
uniprot entry name :
NGAL_RAT
reactivity :
Rat
sequence length :
198
storage stability :
For long term storage, please store the entire kit at -20 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Assay Type: Sandwich. Detection Range: 0.78-50 ng/ml. Sensitivity: 0.46 ng/mL
other info2 :
Intra-Assay CV: <=5.2%. Inter-Assay CV: <=7.4%. Recovery: 91%
ncbi gi num :
18543345
ncbi acc num :
NP_570097.1
ncbi gb acc num :
NM_130741.1
uniprot acc num :
P30152
ncbi mol weight :
22,476 Da
ncbi pathways :
Iron Uptake And Transport Pathway (1333170); Transmembrane Transport Of Small Molecules Pathway (1333125)
ncbi summary :
mouse homolog plays a role in IL3 withdrawal-induced apoptosis [RGD, Feb 2006]
uniprot summary :
LCN2: Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5- DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth. Belongs to the calycin superfamily. Lipocalin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Apoptosis; Transporter; Secreted; Secreted, signal peptide. Cellular Component: cytosol; extracellular region; extracellular space. Molecular Function: iron ion binding; protease binding; protein homodimerization activity; transporter activity. Biological Process: cellular response to nutrient levels; innate immune response; ion transport; iron ion homeostasis; positive regulation of cell projection organization and biogenesis; response to bacterium; response to drug; response to herbicide; response to mycotoxin; response to nutrient levels; response to oxidative stress; response to virus; siderophore transport
size1 :
48-Strip-Wells
price1 :
305 USD
size2 :
96-Strip-Wells
price2 :
395
size3 :
5x96-Strip-Wells
price3 :
1615
size4 :
10x96-Strip-Wells
price4 :
2880
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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