catalog number :
MBS2883482
products type :
ELISA Kit
products full name :
Human Thy-1 membrane glycoprotein ELISA Kit
products short name :
[Thy-1 membrane glycoprotein]
products name syn :
[Thy-1 membrane glycoprotein; CDw90; Thy-1 antigen; THY1; CD90]
other names :
[thy-1 membrane glycoprotein preproprotein; Thy-1 membrane glycoprotein; thy-1 membrane glycoprotein; Thy-1 cell surface antigen; CDw90; Thy-1 antigen; CD_antigen: CD90]
products gene name :
[THY1]
other gene names :
[THY1; THY1; CD90; CDw90]
uniprot entry name :
THY1_HUMAN
specificity :
Recombinant and natural HumanThy-1 membrane glycoprotein
storage stability :
For long term storage, please store the entire kit at -20 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Tissue Homogenates, Cell Culture Supernates Or Other Biological Fluids.
products description :
Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
ncbi acc num :
NP_001298089.1
ncbi gb acc num :
NM_001311160.1
ncbi mol weight :
17,935 Da
ncbi pathways :
Cardiac Progenitor Differentiation Pathway (712094); IL4-mediated Signaling Events Pathway (137933); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494); Amb2 Integrin Signaling Pathway (137945)
ncbi summary :
This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
uniprot summary :
THY1: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. Protein type: Motility/polarity/chemotaxis; Cell adhesion; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 11q23.3. Cellular Component: anchored to external side of plasma membrane; apical plasma membrane; cytosol; dendrite; endoplasmic reticulum; external side of plasma membrane; focal adhesion; growth cone; integral to plasma membrane; lipid raft; myelin sheath; plasma membrane. Molecular Function: GTPase activator activity; integrin binding; protein binding; protein kinase binding. Biological Process: angiogenesis; cell-cell adhesion; cytoskeleton organization and biogenesis; focal adhesion formation; negative regulation of axonogenesis; negative regulation of cell migration; negative regulation of protein kinase activity; negative regulation of T cell receptor signaling pathway; positive regulation of GTPase activity; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of T cell activation; protein amino acid autophosphorylation; retinal cone cell development; T cell receptor signaling pathway
size4 :
10x96-Strip-Wells