catalog number :
MBS2883334
products type :
ELISA Kit
products full name :
Rat Protein Wnt-5a ELISA Kit
products short name :
[Protein Wnt-5a]
products name syn :
[Protein Wnt-5a; Wnt5a; Wnt-5a]
other names :
[Protein Wnt-5a; Protein Wnt-5a; protein Wnt-5a; wingless-type MMTV integration site family, member 5A]
products gene name :
[Wnt5a]
other gene names :
[Wnt5a; Wnt5a; Wnt-5a]
uniprot entry name :
WNT5A_RAT
specificity :
Recombinant and natural Rat WNT5A
storage stability :
For long term storage, please store the entire kit at -20 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: serum, plasma, tissue homogenates?cell culture supernates or other biological fluids. Detection Range: 0.312-20 ng/mL. Sensitivity: <0.156 ng/mL
other info2 :
Intra-assay Precision: Intra-Assay CV: ?6.3%. Inter-assay Precision: Inter-Assay CV: ?9.5%
products description :
Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates?cell culture supernates or other biological fluids.
ncbi mol weight :
42,283 Da
ncbi pathways :
Asymmetric Localization Of PCP Proteins Pathway (1334000); Basal Cell Carcinoma Pathway (83501); Basal Cell Carcinoma Pathway (525); Beta-catenin Independent WNT Signaling Pathway (1333998); Ca2+ Pathway (1334003); HTLV-I Infection Pathway (373894); HTLV-I Infection Pathway (373889); Hedgehog Signaling Pathway (83455); Hedgehog Signaling Pathway (474); Hippo Signaling Pathway (749790)
ncbi summary :
mouse homolog regulates chondrocyte differentiation and proliferation in longitudinal skeletal growth of long bones [RGD, Feb 2006]
uniprot summary :
Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells. Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle. Inhibits type II collagen expression in chondrocytes ().
size4 :
10x96-Strip-Wells