Mouse Neurofilament light polypeptide ELISA Kit | MyBioSource MBS2882932 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Neurofilament light polypeptide ELISA Kit

catalog :

MBS2882932

quantity :

48-Strip-Wells

price :

400 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS2882932

products type :

ELISA Kit

products full name :

Mouse Neurofilament light polypeptide ELISA Kit

products short name :

[Neurofilament light polypeptide]

products name syn :

[Neurofilament light polypeptide; NF-L; 68 kDa neurofilament protein; Neurofilament triplet L protein; Nefl; Nf68; Nfl]

other names :

[neurofilament light polypeptide; Neurofilament light polypeptide; neurofilament light polypeptide; neurofilament, light polypeptide; 68 kDa neurofilament protein; Neurofilament triplet L protein]

products gene name :

[Nefl]

other gene names :

[Nefl; Nefl; Nfl; NF-L; NF68; CMT2E; AI847934; Nf68; Nfl; NF-L]

uniprot entry name :

NFL_MOUSE

reactivity :

Mouse

sequence length :

543

storage stability :

For long term storage, please store the entire kit at -20 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Tissue Homogenates, Cell Culture Supernates Or Other Biological Fluids.

products description :

Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

39204499

ncbi acc num :

NP_035040.1

ncbi gb acc num :

NM_010910.1

uniprot acc num :

P08551

ncbi mol weight :

61,508 Da

ncbi pathways :

ARMS-mediated Activation Pathway (1324638); Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway (1323483); Amyotrophic Lateral Sclerosis (ALS) Pathway (83296); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); Axon Guidance Pathway (1323598); CREB Phosphorylation Through The Activation Of CaMKII Pathway (1323490); CREB Phosphorylation Through The Activation Of Ras Pathway (1323486); Cytokine Signaling In Immune System Pathway (1323763); DAP12 Interactions Pathway (1323743); DAP12 Signaling Pathway (1323744)

uniprot summary :

NFL: one of the three (L, M, and H) intermediate filament proteins that form neurofilaments. Neurofilaments are involved in the maintenance of neuronal caliber. NF-L is the most abundant of the three neurofilament proteins. Defects cause Charcot-Marie-Tooth disease type 1F (CMT1F). Protein type: Cytoskeletal. Cellular Component: axon; cytoplasm; growth cone; intermediate filament; myelin sheath; neurofilament; neuron projection; TSC1-TSC2 complex. Molecular Function: identical protein binding; phospholipase binding; protein binding; protein binding, bridging; protein C-terminus binding; protein domain specific binding; protein heterodimerization activity; structural constituent of cytoskeleton; structural molecule activity. Biological Process: anterograde axon cargo transport; axon regeneration in the peripheral nervous system; axon transport of mitochondrion; intermediate filament bundle assembly; intermediate filament organization; intermediate filament polymerization and/or depolymerization; locomotion; microtubule cytoskeleton organization and biogenesis; negative regulation of neuron apoptosis; neurite morphogenesis; neurofilament bundle assembly; neurofilament cytoskeleton organization and biogenesis; neuromuscular process controlling balance; positive regulation of axonogenesis; protein polymerization; regulation of axon diameter; retrograde axon cargo transport

size1 :

48-Strip-Wells

price1 :

400 USD

size2 :

96-Strip-Wells

price2 :

530

size3 :

5x96-Strip-Wells

price3 :

2305

size4 :

10x96-Strip-Wells

price4 :

4250

more info or order :

MyBioSource product webpage